Hotels in Santa Fe

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Check prices for these dates

Tonight
Dec 12 - Dec 13
Tomorrow
Dec 13 - Dec 14
This weekend
Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

Where to stay in Santa Fe?

Breakfast area
Ayenda Casa San Pablo

Ayenda Casa San Pablo

Ayenda Casa San Pablo
2.5 star property
Santa Fe
8.0 out of 10, Very Good, (7)
The price is CNY434
CNY434 total
Jan 12 - Jan 13, 2026
Ayenda Casa San Pablo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit MedellĂ­n?

Our prices for hotels in MedellĂ­n are cheapest in September
Price trends for hotels in MedellĂ­n
Pricing is based on two traveler single night rates
View properties in December
Currently viewing crowd sizes and weather for December.
Typical weather for MedellĂ­n
December
High crowds
High 24°C / low 13°C. Cloudy most days.
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24°
weather_cloudy
December, High crowds, average high temperature 24 degrees Celsius, average low temperature 13 degrees Celsius. Cloudy most days.
13°
25°
weather_cloudy
January, Moderate crowds, average high temperature 25 degrees Celsius, average low temperature 13 degrees Celsius. Cloudy most days.
13°
25°
weather_cloudy
February, Moderate crowds, average high temperature 25 degrees Celsius, average low temperature 13 degrees Celsius. Cloudy most days.
13°
24°
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March, Moderate crowds, average high temperature 24 degrees Celsius, average low temperature 14 degrees Celsius. Rainy most days.
14°
24°
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April, Low crowds, average high temperature 24 degrees Celsius, average low temperature 14 degrees Celsius. Rainy most days.
14°
24°
weather_sleet
May, Moderate crowds, average high temperature 24 degrees Celsius, average low temperature 14 degrees Celsius. Rainy most days.
14°
25°
weather_sleet
June, Low crowds, average high temperature 25 degrees Celsius, average low temperature 13 degrees Celsius. Rainy most days.
13°
25°
weather_sleet
July, High crowds, average high temperature 25 degrees Celsius, average low temperature 13 degrees Celsius. Rainy most days.
13°
26°
weather_sleet
August, High crowds, average high temperature 26 degrees Celsius, average low temperature 13 degrees Celsius. Rainy most days.
13°
25°
weather_sleet
September, Low crowds, average high temperature 25 degrees Celsius, average low temperature 13 degrees Celsius. Rainy most days.
13°
24°
weather_sleet
October, Low crowds, average high temperature 24 degrees Celsius, average low temperature 13 degrees Celsius. Rainy most days.
13°
23°
weather_sleet
November, High crowds, average high temperature 23 degrees Celsius, average low temperature 13 degrees Celsius. Rainy most days.
13°
Monthly weather averages (˚C)

Top landmarks in Santa Fe

Santa Fe Zoological Park

It's feeding time at the zoo! If you want to be reminded of some of the great animals our world is home to, you might want to pay a trip to Santa Fe Zoological Park, located 1.6 mi (2.6 km) from central MedellĂ­n. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. If you have fun at Santa Fe Zoological Park, you'll love Pueblito Paisa and Medellin Botanical Garden, both located nearby.
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Check out reviews of Santa Fe hotels guests love

V Grand Hotel, a member of Radisson Individuals

V Grand Hotel, a member of Radisson Individuals

10/10 Excellent
"Todo bien"
MARILUZ 2-night trip
Posted 18 hours ago
V Grand Hotel, a member of Radisson Individuals

Frequently asked questions

Is Santa Fe expensive to stay in?
You can find great hotels from CNY367 in Santa Fe to suit a range of budgets. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for Santa Fe hotels?
Discover great deals on hotels in Santa Fe with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Santa Fe hotels.
Can I receive a refund if I cancel my Santa Fe hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Santa Fe hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
What are some of the best pet-friendly hotels in Santa Fe?
Traveling with your pet doesn't mean sacrificing a great hotel stay. In Santa Fe, our travelers love:
  • Hotel Boutique Olaya 54 has an average guest rating of 10 out of 10. To find more pet-friendly stays on Hotels.com, use the "Amenities" filter in your search and select "Pet friendly".
Is it worth staying in Santa Fe?
There are 12 hotels in the area to find your perfect somewhere. Basing yourself in Santa Fe makes it easy to explore MedellĂ­n, including the neighborhoods of El Poblado and Laureles.
Find out more about Santa Fe

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