
Hotels in Santa Clara
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Radisson Hotel Panama Canal
Radisson Hotel Panama Canal4.5 star property
Amador, 13.9 km from Santa Clara
8.4 out of 10, Very Good, (1003)
8.4/10
Very Good
(1003)
The price is CNY593
CNY593
CNY652 total
includes taxes & fees
Jan 3 - Jan 4, 2026




9.0 out of 10, Wonderful, (4687)
9.0/10
Wonderful
(4687)
The price is CNY902
CNY902
CNY993 total
includes taxes & fees
Dec 22 - Dec 23




Ramada Plaza by Wyndham Panama Punta Pacifica
Ramada Plaza by Wyndham Panama Punta Pacifica4.0 star property
San Francisco, 6.6 km from Santa Clara
9.6 out of 10, Exceptional, (1121)
9.6/10
Exceptional
(1121)
The price is CNY766
CNY766
CNY843 total
includes taxes & fees
Jan 16 - Jan 17, 2026




Hyatt Regency Panama City
Hyatt Regency Panama City4.5 star property
Campo Alegre, 8.4 km from Santa Clara
10.0 out of 10, Exceptional, (125)
10/10
Exceptional
(125)
The price is CNY951
CNY951
CNY1,046 total
includes taxes & fees
Dec 20 - Dec 21




9.2 out of 10, Wonderful, (1015)
9.2/10
Wonderful
(1015)




Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG4.0 star property
10.2 km from Santa Clara
8.4 out of 10, Very Good, (2330)
8.4/10
Very Good
(2330)
The price is CNY775
CNY775
CNY852 total
includes taxes & fees
Dec 31 - Jan 1, 2026




Riande Aeropuerto Hotel & Casino
Riande Aeropuerto Hotel & Casino4.0 star property
8.7 km from Santa Clara
8.6 out of 10, Excellent, (1847)
8.6/10
Excellent
(1847)
The price is CNY881
CNY881
CNY969 total
includes taxes & fees
Jan 16 - Jan 17, 2026




The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City5.0 star property
Juan Diaz, 2.8 km from Santa Clara
9.6 out of 10, Exceptional, (638)
9.6/10
Exceptional
(638)
The price is CNY1,579
CNY1,579
CNY1,737 total
includes taxes & fees
Jan 17 - Jan 18, 2026




ORHO HOTEL BOUTIQUE PANAMA Airport
ORHO HOTEL BOUTIQUE PANAMA Airport2.5 star property
9.7 km from Santa Clara
9.0 out of 10, Wonderful, (37)
9.0/10
Wonderful
(37)
The price is CNY845
CNY845
CNY1,097 total
includes taxes & fees
Dec 19 - Dec 20




Principe Hotel and Suites
Principe Hotel and Suites3.0 star property
El Cangrejo, 7.8 km from Santa Clara
9.0 out of 10, Wonderful, (1596)
9.0/10
Wonderful
(1596)
The price is CNY389
CNY389
CNY428 total
includes taxes & fees
Dec 19 - Dec 20




9.4 out of 10, Exceptional, (162)
9.4/10
Exceptional
(162)
The price is CNY500
CNY500
CNY876 total
includes taxes & fees
Jan 3 - Jan 4, 2026




Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel3.5 star property
Punta Paitilla, 8.4 km from Santa Clara
9.4 out of 10, Exceptional, (2137)
9.4/10
Exceptional
(2137)
The price is CNY760
CNY760
CNY836 total
includes taxes & fees
Dec 28 - Dec 29




Megapolis Hotel Panamá
Megapolis Hotel Panamá4.5 star property
Punta Paitilla, 8.2 km from Santa Clara
8.4 out of 10, Very Good, (1278)
8.4/10
Very Good
(1278)
The price is CNY979
CNY979
CNY1,077 total
includes taxes & fees
Dec 19 - Dec 20




8.8 out of 10, Excellent, (1052)
8.8/10
Excellent
(1052)
The price is CNY592
CNY592
CNY652 total
includes taxes & fees
Dec 22 - Dec 23




Summit Rainforest & Golf Resort
Summit Rainforest & Golf Resort4.0 star property
17.8 km from Santa Clara
8.4 out of 10, Very Good, (1001)
8.4/10
Very Good
(1001)
The price is CNY503
CNY503
CNY553 total
includes taxes & fees
Dec 28 - Dec 29




9.2 out of 10, Wonderful, (1023)
9.2/10
Wonderful
(1023)
The price is CNY748
CNY748
CNY823 total
includes taxes & fees
Dec 20 - Dec 21




Courtyard by Marriott Panama Metromall
Courtyard by Marriott Panama Metromall4.0 star property
3.2 km from Santa Clara
8.8 out of 10, Excellent, (1006)
8.8/10
Excellent
(1006)
The price is CNY713
CNY713
CNY784 total
includes taxes & fees
Jan 5 - Jan 6, 2026




8.8 out of 10, Excellent, (415)
8.8/10
Excellent
(415)
The price is CNY680
CNY680
CNY748 total
includes taxes & fees
Jan 11 - Jan 12, 2026




9.0 out of 10, Wonderful, (427)
9.0/10
Wonderful
(427)
The price is CNY282
CNY282
CNY310 total
includes taxes & fees
Dec 24 - Dec 25




10.0 out of 10, Exceptional, (1)
10/10
Exceptional
(1)
The price is CNY824
CNY824
CNY906 total
includes taxes & fees
Dec 28 - Dec 29
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
trending_down When is the best time to visit Panama City?
When is the best time to visit Panama City?Our prices for hotels in Panama City are cheapest in September
When is the best time to visit Panama City?
When is the best time to visit Panama City?
Our prices for hotels in Panama City are cheapest in September
Price trends for hotels in Panama City
Pricing is based on two traveler single night rates
Currently viewing crowd sizes and weather for December.trending_up High crowds
Typical weather for Panama City
December
High 29°C / low 24°C. Cloudy most days.
View properties in December 29°
December, High crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Cloudy most days.
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January, Moderate crowds, average high temperature 30 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
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30°
February, High crowds, average high temperature 30 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
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31°
March, High crowds, average high temperature 31 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
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31°
April, Low crowds, average high temperature 31 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
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30°
May, Low crowds, average high temperature 30 degrees Celsius, average low temperature 25 degrees Celsius. Rainy most days.
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29°
June, Low crowds, average high temperature 29 degrees Celsius, average low temperature 25 degrees Celsius. Rainy most days.
25°
29°
July, High crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
August, Moderate crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
September, Low crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
October, Moderate crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
November, Moderate crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
Monthly weather averages (˚C)
Check out reviews of Santa Clara hotels guests love

Megapolis Hotel Panamá
10/10 Excellent
"Clean room, comfortable, spacious. The breakfast was really good! "

Plaza Paitilla Inn Hotel
10/10 Excellent
"The staff were friendly and helpful. Check in was smooth, room was clean and had a nice view of the bay. The included breakfast buffet was great with a wide selection of foods. I would definitely recommend this hotel."

Crowne Plaza Panama Airport by IHG
10/10 Excellent
"Yes to both"

Decapolis Hotel Panama City
10/10 Excellent
"Nice and clean room. "

Marriott Panama Hotel
10/10 Excellent
"Great hotel and staff!"

Las Americas Golden Tower Panama
10/10 Excellent
"It was a very nice stay. The room is nice, organized and clean with a great view of the city. The blankets are a little too warm and we wished for a lighter blankets. Breakfast buffet was very good with many food choices and best custom eggs cooked tailored to our demands. Uber to Casco Viejo was cheap. Uber to PTY airport was $17. Views from the hotel are beautiful. Pool was the best, clean, lots of lights, cozy and just what we needed to swim after long day of sightseing Panama canal, boat tour to Monkey Islands, long walk along Cinta Costera and dinner with friends on the 5th floor of Golden tower."

Dreams Playa Bonita Panama - All Inclusive
10/10 Excellent
"Excellent service, good even more so. The property is clean, however the chairs and curtains show their age in a major way.
Staff are friendly and every interaction was pleasant. We would definitely return to this resort. "

JW Marriott Panama
10/10 Excellent
"Just a beautiful hotel for any occasion."

Hotel Riu Plaza Panama
10/10 Excellent
"Riu Plaza is the spot. Clean, safe, good location, no complain."
Frequently asked questions
Is Santa Clara expensive to stay in?
You can find great hotels from CNY718 in Santa Clara to suit a range of budgets. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for Santa Clara hotels?
Discover great deals on hotels in Santa Clara with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Santa Clara hotels.
Can I receive a refund if I cancel my Santa Clara hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Santa Clara hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
Is it worth staying in Santa Clara?
Basing yourself in Santa Clara makes it easy to explore Panama City, including the neighborhoods of Bella Vista and San Francisco.
Find out more about Santa Clara
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