Photo by Alice Burghart

Hotels in Cape Girardeau

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Check prices for these dates

Tonight
Dec 20 - Dec 21
Tomorrow
Dec 21 - Dec 22
Next weekend
Dec 26 - Dec 28
In two weeks
Jan 2 - Jan 4

Where to stay in Cape Girardeau?

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Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
9.6 out of 10, Exceptional, (468)
  • cleanliness
    Riverside location with Marriott quality and nearby national forest access.
The price is CNY817
CNY926 total
includes taxes & fees
Dec 29 - Dec 30
Courtyard by Marriott Cape Girardeau Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Budget hotels in Cape Girardeau and vicinity

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Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (685)
The price is CNY406
CNY458 total
includes taxes & fees
Dec 28 - Dec 29
Quality Inn Cape Girardeau North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out hotels with a pool in Cape Girardeau

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Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1005)
The price is CNY634
CNY715 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Drury Plaza Hotel Cape Girardeau Conference Center
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You may also like pet-friendly hotels in Cape Girardeau

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Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1005)
The price is CNY634
CNY715 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Drury Plaza Hotel Cape Girardeau Conference Center
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You can also stay at family-friendly hotels in Cape Girardeau

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Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1005)
The price is CNY634
CNY715 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Drury Plaza Hotel Cape Girardeau Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

When is the best time to visit Cape Girardeau?

Our prices for hotels in Cape Girardeau are cheapest in December
Price trends for hotels in Cape Girardeau
Pricing is based on two traveler single night rates
View properties in December
Currently viewing crowd sizes and weather for December.
Typical weather for Cape Girardeau
December
Low crowds
High 9°C / low 1°C. Partly sunny.
View properties in December
9°
weather_partly_sunny
December, Low crowds, average high temperature 9 degrees Celsius, average low temperature 1 degrees Celsius. Partly sunny.
1°
6°
weather_partly_sunny
January, Low crowds, average high temperature 6 degrees Celsius, average low temperature -2 degrees Celsius. Partly sunny.
-2°
8°
weather_partly_sunny
February, Low crowds, average high temperature 8 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
-1°
14°
weather_sun
March, High crowds, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Sunny most days.
5°
19°
weather_sun
April, High crowds, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
25°
weather_sun
May, High crowds, average high temperature 25 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
30°
weather_sun
June, Moderate crowds, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
32°
weather_sun
July, Moderate crowds, average high temperature 32 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
31°
weather_sun
August, Moderate crowds, average high temperature 31 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
28°
weather_sun
September, Low crowds, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
21°
weather_sun
October, High crowds, average high temperature 21 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
11°
13°
weather_partly_sunny
November, Moderate crowds, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Partly sunny.
4°
Monthly weather averages (˚C)

Top landmarks in Cape Girardeau

Panorama of Academic Hall, Southeast Missouri State University

Southeast Missouri State University

4.4/5 (137 reviews)
If you'd like to get a taste of Cape Girardeau student life, check out Southeast Missouri State University, located 0.9 mi (1.4 km) from central Cape Girardeau.
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View of the Christopher S. Bond Bridge over Missouri River in Kansas City, from the riverfront park

Riverfront Bridge Park

4.4/5 (74 reviews)
Riverfront Bridge Park is worth a visit, located 0.7 mi (1.1 km) from central Cape Girardeau.
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Learn more about Cape Girardeau

Cape Girardeau is well-known for its riverfront and university life while attractions include Isle Casino Cape Girardeau and Show Me Center. Visitors to this family-friendly city speak highly of the restaurants whereas sights include Hunter Valley Winery and Trail of Tears State Park.

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Beautiful city by the Mississippi River
Photo by Alice Burghart
Open Photo by Alice Burghart

Check out reviews of Cape Girardeau hotels guests love

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"The staff was friendly and helpful. Breakfast offered hot and cold selections that were fresh and immaculate cleanliness. Rooms were quiet and good sized. Very clean motel throughout. Ice on each floor, large elevator. laundry available."
LuAnne 1-night trip
Posted 4 days ago
Pear Tree Inn Cape Girardeau West

Frequently asked questions

How much does a hotel room cost in Cape Girardeau?
You can choose a great hotel in Cape Girardeau from CNY452 with properties to suit all budgets and needs. Pear Tree Inn Cape Girardeau West and Pear Tree Inn Cape Girardeau Near the Medical Center are a couple of low-cost options that are popular with our travelers. If you're looking for an affordable hotel in Cape Girardeau that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.
How can I find deals and earn rewards at Cape Girardeau hotels?
Discover great deals on Cape Girardeau hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Cape Girardeau hotels.
Can I book Cape Girardeau hotels with free cancellation?
In order to book a refundable Cape Girardeau hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are some top pet-friendly hotels in Cape Girardeau?
Our travelers' favorite pet-friendly hotels in Cape Girardeau include:You can also use the "Amenities" filter in your search on Hotels.com and check "Pet friendly" to discover more pet-friendly hotels in Cape Girardeau.
What are some of the best kid-friendly hotels in Cape Girardeau?
One of the best Cape Girardeau hotels for kids is Drury Plaza Hotel Cape Girardeau Conference Center. Drury Plaza Hotel Cape Girardeau Conference Center is a kid-friendly hotel with a guest score of 9.6 out of 10 offering family-friendly amenities like an indoor pool and a hot tub, plus free cribs in guestrooms. Explore more kid-friendly hotels in Cape Girardeau by using our "Family friendly" filter in your search on Hotels.com.
What are the top Cape Girardeau hotels with a pool?
For some added luxury, discover the best Cape Girardeau hotels with a pool. Drury Plaza Hotel Cape Girardeau Conference Center is a great hotel with an indoor pool and a guest rating of 9.6 out of 10. Plus, you can make the most of its hot tub and restaurant. Drury Inn & Suites Cape Girardeau is a popular hotel that features an indoor pool along with a hot tub and a free buffet breakfast. To find more stays in Cape Girardeau with a pool, use the "Amenities" filter on Hotels.com in your search and select "Pool".
What are some of the best Cape Girardeau hotels with free parking?
If you're exploring by car, finding a great Cape Girardeau hotel with free parking is a win. Our travelers' favorites include:
What are some popular hotels in central Cape Girardeau?
For hotels in central Cape Girardeau, check out Drury Plaza Hotel Cape Girardeau Conference Center and Courtyard by Marriott Cape Girardeau Downtown. Travelers love Drury Plaza Hotel Cape Girardeau Conference Center for its location, as well as the indoor pool, hot tub and restaurant this hotel offers. Courtyard by Marriott Cape Girardeau Downtown is another popular central hotel with a restaurant, a bar/lounge and a coffee shop/cafe.
Can I book a refundable hotel in Cape Girardeau?
If you need the flexibility to change your travel plans to Cape Girardeau, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Cape Girardeau if I'm looking for an affordable accommodation?
Pear Tree Inn Cape Girardeau Near the Medical Center, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG and Pear Tree Inn Cape Girardeau West are a few accommodations you might want to consider that'll save you money.
Where can I stay in Cape Girardeau if I want a vacation rental instead of a hotel?
If you want a good alternative to a hotel, look over our selection of 22 vacation homes. In addition, you can choose from 16 apartments.
What will the weather in Cape Girardeau be like during my vacation?
July and August are typically the warmest months in Cape Girardeau when the average temp is 76°F. January and February are the coldest months when the average temperature is 40°F. April and March are the months with the most rain.