Hotels in Santa Ana

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Check prices for these dates

Tonight
Dec 14 - Dec 15
Tomorrow
Dec 15 - Dec 16
Next weekend
Dec 19 - Dec 21
In two weeks
Dec 26 - Dec 28

Where to stay in Santa Ana?

Garden view
Hostal Casa Buho

Hostal Casa Buho

Hostal Casa Buho
3.0 star property
Santa Ana
8.6 out of 10, Excellent, (21)
The price is CNY336
CNY410 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hostal Casa Buho
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit Antigua Guatemala?

Our prices for hotels in Antigua Guatemala are cheapest in February
Price trends for hotels in Antigua Guatemala
Pricing is based on two traveler single night rates
View properties in December
Currently viewing crowd sizes and weather for December.
Typical weather for Antigua Guatemala
December
High crowds
High 24°C / low 13°C. Sunny most days.
View properties in December
24°
weather_sun
December, High crowds, average high temperature 24 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
24°
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January, Moderate crowds, average high temperature 24 degrees Celsius, average low temperature 12 degrees Celsius. Sunny most days.
12°
26°
weather_sun
February, High crowds, average high temperature 26 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
27°
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March, High crowds, average high temperature 27 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
14°
27°
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April, Moderate crowds, average high temperature 27 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
16°
25°
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May, Low crowds, average high temperature 25 degrees Celsius, average low temperature 17 degrees Celsius. Rainy most days.
17°
24°
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June, Low crowds, average high temperature 24 degrees Celsius, average low temperature 16 degrees Celsius. Rainy most days.
16°
24°
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July, Moderate crowds, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Rainy most days.
15°
24°
weather_sleet
August, Moderate crowds, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Rainy most days.
15°
24°
weather_sleet
September, Low crowds, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Rainy most days.
15°
23°
weather_sleet
October, Low crowds, average high temperature 23 degrees Celsius, average low temperature 15 degrees Celsius. Rainy most days.
15°
23°
weather_sun
November, High crowds, average high temperature 23 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
14°
Monthly weather averages (˚C)

Check out reviews of Santa Ana hotels guests love

Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

10/10 Excellent
"Stunning property. Beautiful grounds."
Deborah 2-night trip
Posted 2 days ago
Hotel Museo Spa Casa Santo Domingo

Frequently asked questions

Is Santa Ana expensive to stay in?
You can find great hotels from CNY410 in Santa Ana to suit a range of budgets. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for Santa Ana hotels?
Discover great deals on hotels in Santa Ana with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Santa Ana hotels.
Can I receive a refund if I cancel my Santa Ana hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Santa Ana hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
What are some of the top Santa Ana hotels with free parking?
If you're traveling by car, make your life easier by booking a Santa Ana hotel with free parking. Our travelers like:
Is it worth staying in Santa Ana?
There are 17 hotels in the area to find your perfect somewhere. Basing yourself in Santa Ana makes it easy to explore Antigua Guatemala, including the neighborhoods of Historic Center and Barrio de La Concepción.
What are some great hotels in Santa Ana with balconies?
There are some top hotels in Santa Ana that offer rooms with a balcony. Check out Casa Buho B&B which has a high guest score of 9.2 out of 10, and balconies in some rooms. Another popular choice is Hostal Casa Buho, which offers balconies in some rooms and has a great guest score of 8.6.
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