Photo by JG Morris

Hotels in Southeast Missouri

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Check prices for these dates

Tonight
Dec 27 - Dec 28
Tomorrow
Dec 28 - Dec 29
Next weekend
Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11

Where to stay in Southeast Missouri?

Free daily full breakfast
Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 star property
8.4 out of 10, Very Good, (1002)
  • cleanliness
    Stay minutes from Central Park at this inviting hotel with an indoor pool and gym.
The price is CNY530
CNY604 total
includes taxes & fees
Dec 28 - Dec 29
Best Western Plus Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Southeast Missouri, MO

Showing deals for:Jan 9 - Jan 11

Image gallery for The Riverview

Lobby sitting area

The Riverview

4.0 star property
Cape Girardeau
9.4/10Exceptional (477 reviews)
10% off
Price is CNY1,053
CNY2,376 total
includes taxes & fees
The Riverview

Budget hotels in Southeast Missouri and vicinity

Reception
OYO Malden Airport Inn

OYO Malden Airport Inn

OYO Malden Airport Inn
2.5 star property
Malden
7.0 out of 10, Good, (68)
The price is CNY342
CNY411 total
includes taxes & fees
Jan 5 - Jan 6, 2026
OYO Malden Airport Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top landmarks in Central United States

Panorama of Academic Hall, Southeast Missouri State University

Southeast Missouri State University

4.4/5 (137 reviews)
If you'd like to get a taste of Cape Girardeau student life, check out Southeast Missouri State University, located 0.9 mi (1.4 km) from central Cape Girardeau.
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A huge granite boulder located in Elephant Rocks State Park
Photo by Pat Long
Open Photo by Pat Long

Elephant Rocks State Park

4.8/5 (52 reviews)
Elephant Rocks State Park is 5.3 mi (8.5 km) from central Ironton, why not stop by during your stay.
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Learn more about Southeast Missouri

Southeast Missouri is well-known for its wineries and riverfront while attractions include K Bridge Recreation Area and Lake Wappapello State Park. This family-friendly city has something for everyone including its university life, restaurants, and sights like Clearwater Lake and Lake Wappapello.

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Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg: Moark Regional Railroad Museum HOURS: Saturdays 1 p.m. - 4 p.m. It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history. This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! #MTTS2014 #minitakesthestates #go11 #train
Photo by Bill Dillard
Open Photo by Bill Dillard

Check out reviews of Southeast Missouri hotels guests love

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"This our favorite place to stop for a good night sleep. "
Eileen 1-night trip
Posted 6 days ago
Drury Inn & Suites Sikeston, MO

Frequently asked questions

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