Photo by Bill Dillard
Hotels in Southeast Missouri
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Where to stay in Southeast Missouri?

Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
8.0 out of 10, Very Good, (43 reviews)
cleanliness Welcoming roadside retreat with quick access to I-55 and daily breakfast service.
The price is CNY389
CNY444 total
includes taxes & fees
Jan 19 - Jan 20

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,003 reviews)
cleanliness Quiet escape near Cape Girardeau with an indoor pool for year-round enjoyment.
The price is CNY578
CNY612 total
includes taxes & fees
Jan 19 - Jan 20

Rockwood Inn
Rockwood InnCape Girardeau
10.0 out of 10, Exceptional, (19 reviews)
cleanliness Charming inn near Show Me Center with free parking and garden amenities.
The price is CNY1,152
CNY1,300 total
includes taxes & fees
Jan 25 - Jan 26

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very Good, (731 reviews)
cleanliness Enjoy a serene stay in Sikeston, just minutes from Central Park and Depot Museum.
The price is CNY408
CNY465 total
includes taxes & fees
Jan 19 - Jan 20

Pear Tree Inn Sikeston
Pear Tree Inn SikestonSikeston
9.4 out of 10, Exceptional, (1,005 reviews)
cleanliness Quiet, dual pool paradise near Central Park in charming Sikeston.
The price is CNY523
CNY601 total
includes taxes & fees
Jan 22 - Jan 23

Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MOPoplar Bluff
7.8 out of 10, Good, (1,001 reviews)
cleanliness Experience clean comfort near North Main Street Historic District and art museum.
The price is CNY397
CNY419 total
includes taxes & fees
Jan 20 - Jan 21

Best Western Plus Sikeston
Best Western Plus SikestonSikeston
8.4 out of 10, Very Good, (1,003 reviews)
cleanliness Stay minutes from Central Park at this inviting hotel with an indoor pool and gym.
The price is CNY498
CNY567 total
includes taxes & fees
Jan 25 - Jan 26

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (105 reviews)
cleanliness Relax at a modern hotel near Shawnee Forest with a refreshing indoor pool.
The price is CNY623
CNY709 total
includes taxes & fees
Jan 27 - Jan 28

Super 8 by Wyndham Potosi
Super 8 by Wyndham PotosiPotosi
7.0 out of 10, Good, (382 reviews)
cleanliness Convenient lodging in Potosi with free breakfast, WiFi, and ample parking.
The price is CNY385
CNY421 total
includes taxes & fees
Jan 19 - Jan 20

Shepherd Mountain Inn
Shepherd Mountain InnIronton
9.4 out of 10, Exceptional, (304 reviews)
cleanliness Enjoy a peaceful mountain escape with bar, restaurant, and nearby hiking trails.

Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
9.0 out of 10, Wonderful, (578 reviews)
cleanliness Lakeside haven with championship golf and warm service at this serene retreat.
The price is CNY899
CNY1,024 total
includes taxes & fees
Jan 19 - Jan 20

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,009 reviews)
cleanliness Explore the stunning forest views with free breakfast, indoor pool, and dining options.
The price is CNY627
CNY708 total
includes taxes & fees
Jan 22 - Jan 23

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.2 out of 10, Good, (1,002 reviews)
cleanliness Enjoy a peaceful night's rest and complimentary breakfast at this quiet Sikeston hotel.
The price is CNY438
CNY500 total
includes taxes & fees
Jan 25 - Jan 26

Town House Inn
Town House InnJackson
7.6 out of 10, Good, (430 reviews)
cleanliness Comfortable Jackson motel near Litz Park with free parking and helpful staff.
The price is CNY489
CNY530 total
includes taxes & fees
Jan 19 - Jan 20

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,003 reviews)
cleanliness Relaxing indoor pool hotel minutes from Cape Splash and historic Fort D sites.
The price is CNY634
CNY716 total
includes taxes & fees
Jan 25 - Jan 26

Baymont by Wyndham Festus
Baymont by Wyndham FestusFestus
6.8 out of 10, (929 reviews)
The price is CNY565
CNY646 total
includes taxes & fees
Jan 19 - Jan 20

Black River Motel and Restaurant
Black River Motel and RestaurantLesterville
8.4 out of 10, Very Good, (35 reviews)
cleanliness Enjoy a serene Black River retreat with trails for hiking and kayaking nearby.
The price is CNY899
CNY951 total
includes taxes & fees
Jan 19 - Jan 20

The Farmstead Hotel
The Farmstead HotelCaruthersville
8.8 out of 10, Excellent, (474 reviews)
cleanliness Serene and well-maintained riverfront property with gaming excitement and quiet comfort.
The price is CNY530
CNY602 total
includes taxes & fees
Jan 19 - Jan 20

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, (620 reviews)
cleanliness Gateway to historic Charleston with easy interstate access and free breakfast.
The price is CNY433
CNY480 total
includes taxes & fees
Jan 19 - Jan 20

Motel 6 Bonne Terre, MO
Motel 6 Bonne Terre, MOBonne Terre
6.6 out of 10, (29 reviews)
The price is CNY436
CNY477 total
includes taxes & fees
Jan 19 - Jan 20
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Showing deals for:Jan 18 - Jan 19
VIP Access

9.6 out of 10, Exceptional, (84 reviews)
The price is CNY692
per night
CNY753 total
includes taxes & fees
Showing deals for:Jan 23 - Jan 25

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (689 reviews)
CNY253 off
The price is CNY717
per night
CNY1,552 total
includes taxes & fees
Check out pet-friendly hotels in Southeast Missouri

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1009)
The price is CNY627
CNY708 total
includes taxes & fees
Jan 22 - Jan 23
You may also like hotels with hot tubs in Southeast Missouri

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1009)
The price is CNY627
CNY708 total
includes taxes & fees
Jan 22 - Jan 23
You can also stay at hotels with a pool in Southeast Missouri

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1009)
The price is CNY627
CNY708 total
includes taxes & fees
Jan 22 - Jan 23
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Southeast Missouri
Family friendly
Top landmarks in Central United States
Learn more about Southeast Missouri
Southeast Missouri is well-known for its wineries and riverfront while attractions include K Bridge Recreation Area and Lake Wappapello State Park. This family-friendly city has something for everyone including its university life, restaurants, and sights like Clearwater Lake and Lake Wappapello.

Photo by Bill Dillard
Open Photo by Bill Dillard
Check out reviews of Southeast Missouri hotels guests love

Fairfield Inn & Suites by Marriott Poplar Bluff
10/10 Excellent
Frequently asked questions
Keep exploring
- Perryville Hotels
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