Photo by Henry Fitzthum

Hotels in Southeast Missouri

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Check prices for these dates

Tonight
Jan 14 - Jan 15
Tomorrow
Jan 15 - Jan 16
This weekend
Jan 16 - Jan 18
Next weekend
Jan 23 - Jan 25

Where to stay in Southeast Missouri?

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,001 reviews)
The price is CNY628
CNY708 total
includes taxes & fees
Jan 19 - Jan 20
Drury Plaza Hotel Cape Girardeau Conference Center
Indoor pool, outdoor pool
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,000 reviews)
The price is CNY628
CNY722 total
includes taxes & fees
Jan 19 - Jan 20
Drury Inn & Suites Sikeston, MO
Premium bedding, down comforters, pillowtop beds, in-room safe
The Farmstead Hotel
The Farmstead Hotel
The Farmstead Hotel
2.5 star property
Caruthersville
8.8 out of 10, Excellent, (471 reviews)
The price is CNY530
CNY603 total
includes taxes & fees
Jan 30 - Jan 31
The Farmstead Hotel
Blackout drapes, free WiFi, bed sheets
Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
7.8 out of 10, Good, (1,000 reviews)
The price is CNY397
CNY419 total
includes taxes & fees
Jan 21 - Jan 22
Motel 6 Poplar Bluff, MO
Lobby
Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (977 reviews)
The price is CNY726
CNY820 total
includes taxes & fees
Feb 6 - Feb 7
Drury Inn & Suites Poplar Bluff
Individually decorated, individually furnished, desk, blackout drapes
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (729 reviews)
The price is CNY387
CNY441 total
includes taxes & fees
Jan 21 - Jan 22
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (149 reviews)
The price is CNY614
CNY693 total
includes taxes & fees
Jan 25 - Jan 26
Fairfield Inn & Suites by Marriott Cape Girardeau
Exterior
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (686 reviews)
The price is CNY587
CNY635 total
includes taxes & fees
Jan 19 - Jan 20
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Free daily buffet breakfast
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,006 reviews)
The price is CNY628
CNY708 total
includes taxes & fees
Jan 19 - Jan 20
Drury Inn & Suites Cape Girardeau
Free daily full breakfast
Best Western Plus Sikeston
Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1,009 reviews)
The price is CNY468
CNY534 total
includes taxes & fees
Jan 18 - Jan 19
Best Western Plus Sikeston
Front of property
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,004 reviews)
The price is CNY523
CNY590 total
includes taxes & fees
Jan 15 - Jan 16
Pear Tree Inn Cape Girardeau Near the Medical Center
Lobby
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,004 reviews)
The price is CNY579
CNY612 total
includes taxes & fees
Jan 19 - Jan 20
Drury Inn & Suites Jackson MO
Indoor pool
Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature Collection
2.5 star property
Farmington
9.0 out of 10, Wonderful, (578 reviews)
The price is CNY900
CNY1,024 total
includes taxes & fees
Jan 20 - Jan 21
Crown Pointe Lodge, BW Signature Collection
Front of property
Echo Bluff State Park
Echo Bluff State Park
Echo Bluff State Park
2.5 star property
Eminence
9.4 out of 10, Exceptional, (219 reviews)
The price is CNY1,144
CNY1,209 total
includes taxes & fees
Jan 20 - Jan 21
Echo Bluff State Park
Reception
Hampton Inn Poplar Bluff
Hampton Inn Poplar Bluff
Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (798 reviews)
The price is CNY761
CNY853 total
includes taxes & fees
Feb 14 - Feb 15
Hampton Inn Poplar Bluff
Lobby sitting area
EC Reed's Mercantile and Hotel
EC Reed's Mercantile and Hotel
EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (84 reviews)
EC Reed's Mercantile and Hotel
Reception
Hampton Inn By Hilton Dexter
Hampton Inn By Hilton Dexter
Hampton Inn By Hilton Dexter
2.5 star property
Dexter
10.0 out of 10, Exceptional, (8 reviews)
The price is CNY738
CNY828 total
includes taxes & fees
Jan 23 - Jan 24
Hampton Inn By Hilton Dexter
Hiking
Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain View
3.0 star property
Mountain View
8.6 out of 10, Excellent, (336 reviews)
The price is CNY628
CNY680 total
includes taxes & fees
Jan 18 - Jan 19
Honeysuckle Inn - Mountain View
Desk, blackout drapes, rollaway beds, free WiFi
Fort Davidson Hotel
Fort Davidson Hotel
Fort Davidson Hotel
2.5 star property
Ironton
9.2 out of 10, Wonderful, (175 reviews)
The price is CNY837
CNY914 total
includes taxes & fees
Jan 17 - Jan 18
Fort Davidson Hotel
Indoor pool, outdoor pool
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1,001 reviews)
The price is CNY523
CNY601 total
includes taxes & fees
Jan 21 - Jan 22
Pear Tree Inn Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Budget hotels in Southeast Missouri and vicinity

Premium bedding, desk, iron/ironing board, free cribs/infant beds
Quality Inn Farmington

Quality Inn Farmington

Quality Inn Farmington
2.5 star property
Farmington
7.6 out of 10, Good, (866)
The price is CNY356
CNY425 total
includes taxes & fees
Feb 1 - Feb 2
Quality Inn Farmington
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Get last-minute hotel deals in Southeast Missouri and save more

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Showing deals for:Jan 14 - Jan 15
Lobby sitting area
The Riverview

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (489 reviews)
We have 1 left at
The price is CNY672
per night
CNY758 total
includes taxes & fees
The Riverview
Showing deals for:Jan 15 - Jan 16
Lobby sitting area
The Riverview

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (489 reviews)
We have 1 left at
The price is CNY672
per night
CNY758 total
includes taxes & fees
The Riverview
Showing deals for:Jan 23 - Jan 25
Hiking
Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
3.0 star property
Mountain View
8.6 out of 10, Excellent, (336 reviews)
CNY232 off
The price is CNY658
per night
CNY1,427 total
includes taxes & fees
Honeysuckle Inn - Mountain View

Check out hotels with a hot tub in Southeast Missouri

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
The price is CNY628
CNY708 total
includes taxes & fees
Jan 19 - Jan 20
Drury Plaza Hotel Cape Girardeau Conference Center
View all properties

You may also like pet-friendly hotels in Southeast Missouri

Lobby
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1004)
The price is CNY579
CNY612 total
includes taxes & fees
Jan 19 - Jan 20
Drury Inn & Suites Jackson MO
View all properties

You can also stay at hotels with a pool in Southeast Missouri

Free daily full breakfast
Best Western Plus Sikeston

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1009)
The price is CNY468
CNY534 total
includes taxes & fees
Jan 18 - Jan 19
Best Western Plus Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top landmarks in Central United States

Panorama of Academic Hall, Southeast Missouri State University

Southeast Missouri State University

4.4/5 (137 reviews)
If you'd like to get a taste of Cape Girardeau student life, check out Southeast Missouri State University, located 0.9 mi (1.4 km) from central Cape Girardeau.
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A huge granite boulder located in Elephant Rocks State Park
Photo by Pat Long
Open Photo by Pat Long

Elephant Rocks State Park

4.8/5 (52 reviews)
Elephant Rocks State Park is 5.3 mi (8.5 km) from central Ironton, why not stop by during your stay.
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Learn more about Southeast Missouri

Southeast Missouri is well-known for its wineries and riverfront while attractions include K Bridge Recreation Area and Lake Wappapello State Park. This family-friendly city has something for everyone including its university life, restaurants, and sights like Clearwater Lake and Lake Wappapello.

See all hotels in Southeast Missouri
Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg: Moark Regional Railroad Museum HOURS: Saturdays 1 p.m. - 4 p.m. It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history. This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! #MTTS2014 #minitakesthestates #go11 #train
Photo by Bill Dillard
Open Photo by Bill Dillard

Check out reviews of Southeast Missouri hotels guests love

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

10/10 Excellent
"The King Suite is huge!"
Gregory J 1-night trip
Posted 4 days ago
Baymont Inn and Suites by Wyndham Farmington, MO

Frequently asked questions

Why should I book my Southeast Missouri accommodation with Hotels.com?
There are plenty of reasons to book your Southeast Missouri travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.