Hotels in Mayo Clinic

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Tonight
Dec 31 - Jan 1
Tomorrow
Jan 1 - Jan 2
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Where to stay in Mayo Clinic?

Lobby lounge
Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
Mayo Clinic
8.2 out of 10, Very Good, (1066)
The price is CNY867
CNY989 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Sonesta Select Scottsdale at Mayo Clinic Campus
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit Mayo Clinic?

Our prices for hotels in Mayo Clinic are cheapest in July
Price trends for hotels in Mayo Clinic
Pricing is based on two traveler single night rates
View properties in December
Currently viewing crowd sizes and weather for December.
Typical weather for Scottsdale
December
Moderate crowds
High 19°C / low 8°C. Sunny most days.
View properties in December
19°
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December, Moderate crowds, average high temperature 19 degrees Celsius, average low temperature 8 degrees Celsius. Sunny most days.
8°
19°
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January, Moderate crowds, average high temperature 19 degrees Celsius, average low temperature 7 degrees Celsius. Sunny most days.
7°
21°
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February, High crowds, average high temperature 21 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
25°
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March, High crowds, average high temperature 25 degrees Celsius, average low temperature 12 degrees Celsius. Sunny most days.
12°
30°
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April, High crowds, average high temperature 30 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
16°
34°
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May, High crowds, average high temperature 34 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
40°
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June, Moderate crowds, average high temperature 40 degrees Celsius, average low temperature 25 degrees Celsius. Sunny most days.
25°
40°
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July, Low crowds, average high temperature 40 degrees Celsius, average low temperature 29 degrees Celsius. Sunny most days.
29°
40°
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August, Low crowds, average high temperature 40 degrees Celsius, average low temperature 29 degrees Celsius. Sunny most days.
29°
37°
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September, Low crowds, average high temperature 37 degrees Celsius, average low temperature 26 degrees Celsius. Sunny most days.
26°
31°
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October, Low crowds, average high temperature 31 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
19°
25°
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November, Moderate crowds, average high temperature 25 degrees Celsius, average low temperature 12 degrees Celsius. Sunny most days.
12°
Monthly weather averages (˚C)

Check out reviews of Mayo Clinic hotels guests love

FOUNDRE Phoenix

FOUNDRE Phoenix

10/10 Excellent
"My stay at Foundre was highlighted by an exceptional guest room that featured stunning, unobstructed views of the city. The property’s commitment to cleanliness and high-end service, combined with such a picturesque backdrop, provided a truly elevated experience.""
Dario 1-night trip
Posted 1 day ago
FOUNDRE Phoenix

Frequently asked questions

Is Mayo Clinic expensive to stay in?
You can find great hotels from CNY674 in Mayo Clinic to suit a range of budgets. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for Mayo Clinic hotels?
Discover great deals on hotels in Mayo Clinic with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Mayo Clinic hotels.
Can I receive a refund if I cancel my Mayo Clinic hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Mayo Clinic hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
What are some of the best pet-friendly hotels in Mayo Clinic?
Traveling with your pet doesn't mean sacrificing a great hotel stay. In Mayo Clinic, our travelers love:
What are some of the best Mayo Clinic hotels with a pool?
Book a Mayo Clinic hotel with a pool for some added relaxation or exercise on your trip. Sonesta Select Scottsdale at Mayo Clinic Campus is a top-rated hotel with an outdoor pool, and an average guest score of 8.2 out of 10. This hotel also features a hot tub and a restaurant. For more Mayo Clinic hotels with a pool, use the "Amenities" filter in your search and select "Pool" on Hotels.com.
Is it worth staying in Mayo Clinic?
There are 14 hotels in the area to find your perfect somewhere. Basing yourself in Mayo Clinic makes it easy to explore Scottsdale, including the neighborhoods of Central Scottsdale and McDowell Mountain Ranch.
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