Hotels in South Main

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Check prices for these dates

Tonight
Jan 8 - Jan 9
Tomorrow
Jan 9 - Jan 10
This weekend
Jan 9 - Jan 11
Next weekend
Jan 16 - Jan 18

Where to stay in South Main?

Premium bedding, pillowtop beds, in-room safe, individually decorated
Wyndham Houston near NRG Park/Medical Center

Wyndham Houston near NRG Park/Medical Center

Wyndham Houston near NRG Park/Medical Center
3.5 star property
South Main
7.2 out of 10, Good, (1202)
The price is CNY901
CNY1,054 total
includes taxes & fees
Jan 20 - Jan 21
Wyndham Houston near NRG Park/Medical Center
Lobby
Wingate Houston near NRG Park/Medical Center

Wingate Houston near NRG Park/Medical Center

Wingate Houston near NRG Park/Medical Center
3.0 star property
South Main
6.6 out of 10, (995)
The price is CNY761
CNY891 total
includes taxes & fees
Jan 21 - Jan 22
Wingate Houston near NRG Park/Medical Center
Hypo-allergenic bedding, in-room safe, individually decorated
Quality Inn & Suites NRG Park - Medical Center

Quality Inn & Suites NRG Park - Medical Center

Quality Inn & Suites NRG Park - Medical Center
2.5 star property
South Main
6.6 out of 10, (1000)
The price is CNY404
CNY473 total
includes taxes & fees
Feb 8 - Feb 9
Quality Inn & Suites NRG Park - Medical Center
Individually decorated, individually furnished, desk, laptop workspace
Comfort Suites Houston near Medical Center- NRG Stadium

Comfort Suites Houston near Medical Center- NRG Stadium

Comfort Suites Houston near Medical Center- NRG Stadium
2.5 star property
South Main
8.6 out of 10, Excellent, (1009)
The price is CNY598
CNY699 total
includes taxes & fees
Jan 9 - Jan 10
Comfort Suites Houston near Medical Center- NRG Stadium
Exterior
Candlewood Suites Houston Medical Center by IHG

Candlewood Suites Houston Medical Center by IHG

Candlewood Suites Houston Medical Center by IHG
2.5 star property
South Main
7.4 out of 10, Good, (829)
The price is CNY545
CNY637 total
includes taxes & fees
Jan 21 - Jan 22
Candlewood Suites Houston Medical Center by IHG
Bar (on property)
SpringHill Suites Houston Medical Center/NRG Park

SpringHill Suites Houston Medical Center/NRG Park

SpringHill Suites Houston Medical Center/NRG Park
3.0 star property
Astrodome, 2.4 km from South Main
9.0 out of 10, Wonderful, (1001)
The price is CNY707
CNY827 total
includes taxes & fees
Jan 25 - Jan 26
SpringHill Suites Houston Medical Center/NRG Park
Free daily continental breakfast
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
2.5 star property
1.4 km from South Main
9.4 out of 10, Exceptional, (1001)
The price is CNY873
CNY1,027 total
includes taxes & fees
Jan 21 - Jan 22
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
Lobby
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center
3.0 star property
Texas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (2233)
The price is CNY820
CNY964 total
includes taxes & fees
Jan 17 - Jan 18
Hyatt Place Houston Medical Center
Lobby
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center, 3.5 km from South Main
9.0 out of 10, Wonderful, (3637)
The price is CNY921
CNY1,078 total
includes taxes & fees
Feb 8 - Feb 9
Blossom Hotel Houston, Curio Collection by Hilton
Outdoor pool, free cabanas, pool umbrellas
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center, 4.4 km from South Main
9.2 out of 10, Wonderful, (1046)
The price is CNY1,011
CNY1,258 total
includes taxes & fees
Jan 11 - Jan 12
The Westin Houston Medical Center/Museum District
Lobby
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

Hyatt House Houston Medical Center
3.0 star property
Texas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (1214)
The price is CNY768
CNY904 total
includes taxes & fees
Feb 7 - Feb 8
Hyatt House Houston Medical Center
Exterior
InterContinental Houston by IHG

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
Texas Medical Center, 4.1 km from South Main
9.2 out of 10, Wonderful, (1004)
The price is CNY1,091
CNY1,416 total
includes taxes & fees
Jan 18 - Jan 19
InterContinental Houston by IHG
Lobby
Hampton Inn & Suites Houston Medical Center NRG Park

Hampton Inn & Suites Houston Medical Center NRG Park

Hampton Inn & Suites Houston Medical Center NRG Park
2.5 star property
Texas Medical Center, 3 km from South Main
8.2 out of 10, Very Good, (1000)
The price is CNY711
CNY836 total
includes taxes & fees
Jan 18 - Jan 19
Hampton Inn & Suites Houston Medical Center NRG Park
Terrace/patio
Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX
3.0 star property
Texas Medical Center, 4.7 km from South Main
9.4 out of 10, Exceptional, (1000)
The price is CNY797
CNY932 total
includes taxes & fees
Jan 18 - Jan 19
Hilton Garden Inn Houston Medical Center, TX
Outdoor pool, open 9:00 AM to 10:00 PM, sun loungers
Crowne Plaza Houston Med Ctr-Galleria Area by IHG

Crowne Plaza Houston Med Ctr-Galleria Area by IHG

Crowne Plaza Houston Med Ctr-Galleria Area by IHG
3.5 star property
6.5 km from South Main
7.6 out of 10, Good, (1299)
The price is CNY454
CNY531 total
includes taxes & fees
Feb 8 - Feb 9
Crowne Plaza Houston Med Ctr-Galleria Area by IHG
Terrace/patio
Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX
3.0 star property
Texas Medical Center, 4.7 km from South Main
9.4 out of 10, Exceptional, (581)
The price is CNY912
CNY1,067 total
includes taxes & fees
Jan 17 - Jan 18
Home2 Suites by Hilton Houston Medical Center, TX
Presidential Suite, 1 King Bed | Premium bedding, in-room safe, desk, iron/ironing board
DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza
4.0 star property
6.6 km from South Main
8.4 out of 10, Very Good, (1417)
The price is CNY797
CNY932 total
includes taxes & fees
Jan 16 - Jan 17
DoubleTree by Hilton Hotel Houston - Greenway Plaza
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, sun loungers
Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria
4.0 star property
8.7 km from South Main
9.0 out of 10, Wonderful, (1194)
The price is CNY1,126
CNY1,530 total
includes taxes & fees
Jan 23 - Jan 24
Hyatt Regency Houston/Galleria
Terrace/patio
Holiday Inn Express Houston - Galleria Area by IHG

Holiday Inn Express Houston - Galleria Area by IHG

Holiday Inn Express Houston - Galleria Area by IHG
2.5 star property
The Galleria, 8.6 km from South Main
9.4 out of 10, Exceptional, (1000)
The price is CNY811
CNY949 total
includes taxes & fees
Jan 25 - Jan 26
Holiday Inn Express Houston - Galleria Area by IHG
Staircase
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria
4.0 star property
The Galleria, 8.8 km from South Main
8.4 out of 10, Very Good, (1532)
The price is CNY1,041
CNY1,218 total
includes taxes & fees
Jan 11 - Jan 12
The Royal Sonesta Houston Galleria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

When is the best time to visit South Main?

Our prices for hotels in South Main are cheapest in February
Price trends for hotels in South Main
Pricing is based on two traveler single night rates
View properties in January
Currently viewing crowd sizes and weather for January.
Typical weather for Houston
January
High 17°C / low 8°C. Sunny most days.
View properties in January
17°
weather_sun
January, no crowd data, average high temperature 17 degrees Celsius, average low temperature 8 degrees Celsius. Sunny most days.
8°
19°
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February, no crowd data, average high temperature 19 degrees Celsius, average low temperature 10 degrees Celsius. Cloudy most days.
10°
23°
weather_sun
March, no crowd data, average high temperature 23 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
14°
26°
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April, no crowd data, average high temperature 26 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
30°
weather_sun
May, no crowd data, average high temperature 30 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
33°
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June, no crowd data, average high temperature 33 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
34°
weather_sun
July, no crowd data, average high temperature 34 degrees Celsius, average low temperature 25 degrees Celsius. Sunny most days.
25°
34°
weather_sun
August, no crowd data, average high temperature 34 degrees Celsius, average low temperature 26 degrees Celsius. Sunny most days.
26°
32°
weather_sun
September, no crowd data, average high temperature 32 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
28°
weather_sun
October, no crowd data, average high temperature 28 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
19°
22°
weather_sun
November, no crowd data, average high temperature 22 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
18°
weather_sun
December, no crowd data, average high temperature 18 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
Monthly weather averages (˚C)

Check out reviews of South Main hotels guests love

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

10/10 Excellent
"New, clean"
MINH THANG 3-night trip
Posted 18 hours ago
Blossom Hotel Houston, Curio Collection by Hilton

Frequently asked questions

Is South Main expensive to stay in?
You can find great hotels from CNY473 in South Main to suit a range of budgets. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for South Main hotels?
Discover great deals on hotels in South Main with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on South Main hotels.
Can I receive a refund if I cancel my South Main hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some South Main hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
What are some of the best pet-friendly hotels in South Main?
Traveling with your pet doesn't mean sacrificing a great hotel stay. In South Main, our travelers love:
What are some of the best South Main hotels for couples?
One of the best South Main hotels for couples is Wingate Houston near NRG Park/Medical Center. Wingate Houston near NRG Park/Medical Center is a popular hotel with an outdoor pool. Find more romantic South Main hotels by using the "Traveler experience" filter in your search and selecting "Adults only" or "Romantic".
What are some of the best South Main hotels with a pool?
Book a South Main hotel with a pool for some added relaxation or exercise on your trip. Wyndham Houston near NRG Park/Medical Center is a top-rated hotel with an outdoor pool, and an average guest score of 7.2 out of 10. This hotel also features a restaurant and a bar/lounge. Wingate Houston near NRG Park/Medical Center is another great hotel that features an outdoor pool, along with a free continental breakfast and a gym. For more South Main hotels with a pool, use the "Amenities" filter in your search and select "Pool" on Hotels.com.
Is it worth staying in South Main?
You're spoilt for choice with 63 hotels in the area so it's easy to find your perfect somewhere. Basing yourself in South Main makes it easy to explore Houston, including the neighborhoods of The Galleria and Texas Medical Center.
Which station is best for South Main?
The main station in South Main is Fannin South Station. If you're staying at a hotel in South Main, check out the nearest station so that you can get around and explore with ease.
Find out more about South Main

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