Hotels in South Main

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Check prices for these dates

Tonight
Jan 12 - Jan 13
Tomorrow
Jan 13 - Jan 14
This weekend
Jan 16 - Jan 18
Next weekend
Jan 23 - Jan 25

Where to stay in South Main?

Hypo-allergenic bedding, in-room safe, individually decorated
Quality Inn & Suites NRG Park - Medical Center

Quality Inn & Suites NRG Park - Medical Center

Quality Inn & Suites NRG Park - Medical Center
2.5 star property
South Main
6.6 out of 10, (1,001 reviews)
The price is CNY434
CNY508 total
includes taxes & fees
Feb 12 - Feb 13
Quality Inn & Suites NRG Park - Medical Center
Lobby
Wingate Houston near NRG Park/Medical Center

Wingate Houston near NRG Park/Medical Center

Wingate Houston near NRG Park/Medical Center
3.0 star property
South Main
6.6 out of 10, (996 reviews)
The price is CNY685
CNY801 total
includes taxes & fees
Jan 26 - Jan 27
Wingate Houston near NRG Park/Medical Center
Premium bedding, pillowtop beds, in-room safe, individually decorated
Wyndham Houston near NRG Park/Medical Center

Wyndham Houston near NRG Park/Medical Center

Wyndham Houston near NRG Park/Medical Center
3.5 star property
South Main
7.2 out of 10, Good, (1,204 reviews)
The price is CNY810
CNY948 total
includes taxes & fees
Jan 20 - Jan 21
Wyndham Houston near NRG Park/Medical Center
Individually decorated, individually furnished, desk, laptop workspace
Comfort Suites Houston near Medical Center- NRG Stadium

Comfort Suites Houston near Medical Center- NRG Stadium

Comfort Suites Houston near Medical Center- NRG Stadium
2.5 star property
South Main
8.6 out of 10, Excellent, (1,014 reviews)
The price is CNY652
CNY763 total
includes taxes & fees
Feb 8 - Feb 9
Comfort Suites Houston near Medical Center- NRG Stadium
Exterior
Candlewood Suites Houston Medical Center by IHG

Candlewood Suites Houston Medical Center by IHG

Candlewood Suites Houston Medical Center by IHG
2.5 star property
South Main
7.4 out of 10, Good, (829 reviews)
The price is CNY544
CNY637 total
includes taxes & fees
Jan 15 - Jan 16
Candlewood Suites Houston Medical Center by IHG
Lobby
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center
3.0 star property
Texas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (2,247 reviews)
The price is CNY819
CNY963 total
includes taxes & fees
Jan 18 - Jan 19
Hyatt Place Houston Medical Center
Free daily continental breakfast
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
2.5 star property
1.4 km from South Main
9.4 out of 10, Exceptional, (1,002 reviews)
The price is CNY872
CNY1,026 total
includes taxes & fees
Jan 18 - Jan 19
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
Lobby
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center, 3.5 km from South Main
9.0 out of 10, Wonderful, (3,654 reviews)
The price is CNY967
CNY1,131 total
includes taxes & fees
Jan 22 - Jan 23
Blossom Hotel Houston, Curio Collection by Hilton
Outdoor pool, free cabanas, pool umbrellas
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center, 4.4 km from South Main
9.2 out of 10, Wonderful, (1,057 reviews)
The price is CNY831
CNY1,034 total
includes taxes & fees
Jan 18 - Jan 19
The Westin Houston Medical Center/Museum District
Lobby
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

Hyatt House Houston Medical Center
3.0 star property
Texas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (1,217 reviews)
The price is CNY768
CNY903 total
includes taxes & fees
Feb 6 - Feb 7
Hyatt House Houston Medical Center
Terrace/patio
Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX
3.0 star property
Texas Medical Center, 4.7 km from South Main
9.4 out of 10, Exceptional, (1,006 reviews)
The price is CNY795
CNY931 total
includes taxes & fees
Jan 18 - Jan 19
Hilton Garden Inn Houston Medical Center, TX
Lobby
Hampton Inn & Suites Houston Medical Center NRG Park

Hampton Inn & Suites Houston Medical Center NRG Park

Hampton Inn & Suites Houston Medical Center NRG Park
2.5 star property
Texas Medical Center, 3 km from South Main
8.2 out of 10, Very Good, (1,007 reviews)
The price is CNY710
CNY834 total
includes taxes & fees
Jan 18 - Jan 19
Hampton Inn & Suites Houston Medical Center NRG Park
Outdoor pool, open 9:00 AM to 10:00 PM, sun loungers
Crowne Plaza Houston Med Ctr-Galleria Area by IHG

Crowne Plaza Houston Med Ctr-Galleria Area by IHG

Crowne Plaza Houston Med Ctr-Galleria Area by IHG
3.5 star property
6.5 km from South Main
7.6 out of 10, Good, (1,311 reviews)
The price is CNY454
CNY531 total
includes taxes & fees
Feb 9 - Feb 10
Crowne Plaza Houston Med Ctr-Galleria Area by IHG
Terrace/patio
Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX
3.0 star property
Texas Medical Center, 4.7 km from South Main
9.4 out of 10, Exceptional, (584 reviews)
The price is CNY910
CNY1,065 total
includes taxes & fees
Jan 18 - Jan 19
Home2 Suites by Hilton Houston Medical Center, TX
Presidential Suite, 1 King Bed | Premium bedding, in-room safe, desk, iron/ironing board
DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza
4.0 star property
6.6 km from South Main
8.4 out of 10, Very Good, (1,427 reviews)
The price is CNY795
CNY931 total
includes taxes & fees
Jan 18 - Jan 19
DoubleTree by Hilton Hotel Houston - Greenway Plaza
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, sun loungers
Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria
4.0 star property
8.7 km from South Main
9.0 out of 10, Wonderful, (1,196 reviews)
The price is CNY1,061
CNY1,453 total
includes taxes & fees
Jan 29 - Jan 30
Hyatt Regency Houston/Galleria
Suite, 1 Bedroom | In-room safe, desk, blackout drapes, iron/ironing board
Hyatt Place Houston/Galleria

Hyatt Place Houston/Galleria

Hyatt Place Houston/Galleria
3.0 star property
8.7 km from South Main
8.8 out of 10, Excellent, (1,332 reviews)
The price is CNY942
CNY1,107 total
includes taxes & fees
Jan 18 - Jan 19
Hyatt Place Houston/Galleria
Staircase
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria
4.0 star property
The Galleria, 8.8 km from South Main
8.4 out of 10, Very Good, (1,546 reviews)
The price is CNY1,110
CNY1,298 total
includes taxes & fees
Jan 18 - Jan 19
The Royal Sonesta Houston Galleria
Terrace/patio
Holiday Inn Express Houston - Galleria Area by IHG

Holiday Inn Express Houston - Galleria Area by IHG

Holiday Inn Express Houston - Galleria Area by IHG
2.5 star property
The Galleria, 8.6 km from South Main
9.4 out of 10, Exceptional, (1,005 reviews)
The price is CNY851
CNY996 total
includes taxes & fees
Feb 12 - Feb 13
Holiday Inn Express Houston - Galleria Area by IHG
Lobby
Sonesta ES Suites Houston Galleria

Sonesta ES Suites Houston Galleria

Sonesta ES Suites Houston Galleria
3.0 star property
The Galleria, 8.4 km from South Main
8.2 out of 10, Very Good, (1,147 reviews)
The price is CNY706
CNY826 total
includes taxes & fees
Jan 13 - Jan 14
Sonesta ES Suites Houston Galleria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit South Main?

Our prices for hotels in South Main are cheapest in February
Price trends for hotels in South Main
Pricing is based on two traveler single night rates
View properties in January
Currently viewing crowd sizes and weather for January.
Typical weather for Houston
January
High 17°C / low 8°C. Sunny most days.
View properties in January
17°
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January, no crowd data, average high temperature 17 degrees Celsius, average low temperature 8 degrees Celsius. Sunny most days.
8°
19°
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February, no crowd data, average high temperature 19 degrees Celsius, average low temperature 10 degrees Celsius. Cloudy most days.
10°
23°
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March, no crowd data, average high temperature 23 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
14°
26°
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April, no crowd data, average high temperature 26 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
30°
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May, no crowd data, average high temperature 30 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
33°
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June, no crowd data, average high temperature 33 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
34°
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July, no crowd data, average high temperature 34 degrees Celsius, average low temperature 25 degrees Celsius. Sunny most days.
25°
34°
weather_sun
August, no crowd data, average high temperature 34 degrees Celsius, average low temperature 26 degrees Celsius. Sunny most days.
26°
32°
weather_sun
September, no crowd data, average high temperature 32 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
28°
weather_sun
October, no crowd data, average high temperature 28 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
19°
22°
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November, no crowd data, average high temperature 22 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
18°
weather_sun
December, no crowd data, average high temperature 18 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
Monthly weather averages (˚C)

Check out reviews of South Main hotels guests love

Hilton Americas-Houston

Hilton Americas-Houston

10/10 Excellent
"AAA"
Che 1-night trip
Posted 20 hours ago
Hilton Americas-Houston

Frequently asked questions

Is South Main expensive to stay in?
You can find great hotels from CNY508 in South Main to suit a range of budgets. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for South Main hotels?
Discover great deals on hotels in South Main with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on South Main hotels.
Can I receive a refund if I cancel my South Main hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some South Main hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
What are some of the best pet-friendly hotels in South Main?
Traveling with your pet doesn't mean sacrificing a great hotel stay. In South Main, our travelers love:
What are some of the best South Main hotels for couples?
One of the best South Main hotels for couples is Wingate Houston near NRG Park/Medical Center. Wingate Houston near NRG Park/Medical Center is a popular hotel with an outdoor pool. Find more romantic South Main hotels by using the "Traveler experience" filter in your search and selecting "Adults only" or "Romantic".
What are some of the best South Main hotels with a pool?
Book a South Main hotel with a pool for some added relaxation or exercise on your trip. Wyndham Houston near NRG Park/Medical Center is a top-rated hotel with an outdoor pool, and an average guest score of 7.2 out of 10. This hotel also features a restaurant and a bar/lounge. Wingate Houston near NRG Park/Medical Center is another great hotel that features an outdoor pool, along with a free continental breakfast and a gym. For more South Main hotels with a pool, use the "Amenities" filter in your search and select "Pool" on Hotels.com.
Is it worth staying in South Main?
You're spoilt for choice with 63 hotels in the area so it's easy to find your perfect somewhere. Basing yourself in South Main makes it easy to explore Houston, including the neighborhoods of The Galleria and Texas Medical Center.
Which station is best for South Main?
The main station in South Main is Fannin South Station. If you're staying at a hotel in South Main, check out the nearest station so that you can get around and explore with ease.
Find out more about South Main

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