Hotels near Enterprise Center St. Louis

Q: What are the best hotels near Enterprise Center?

Guests love staying at 21C Museum Hotel St Louis , which is a hotel near Enterprise Center. OYO Hotel St. Louis Downtown City Center MO is another well-reviewed hotel and is just steps away. The area has plenty to choose from with 2,097 lodging options including hotels and vacation rentals.

Where to?

Dates

January 2026

February 2026

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Where to stay near Enterprise Center?

Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 1.2 km from Enterprise Center

CNY1,174 total

includes taxes & fees

Jan 22 - Jan 23

Drury Inn & Suites St. Louis Union Station

Downtown West, 0.6 km from Enterprise Center

CNY986 total

includes taxes & fees

Jan 22 - Jan 23

Four Seasons Hotel St Louis

1.8 km from Enterprise Center

CNY3,382 total

includes taxes & fees

Jan 19 - Jan 20

Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West, 0.9 km from Enterprise Center

CNY892 total

includes taxes & fees

Feb 16 - Feb 17

Live by Loews - St.Louis

Downtown St. Louis, 0.8 km from Enterprise Center

CNY1,235 total

includes taxes & fees

Jan 25 - Jan 26

Grand Center Inn

3.1 km from Enterprise Center

CNY1,471 total

includes taxes & fees

Jan 19 - Jan 20

21C Museum Hotel St Louis

Downtown West, 0.5 km from Enterprise Center

CNY1,206 total

includes taxes & fees

Feb 8 - Feb 9

Pear Tree Inn St. Louis Near Union Station

Downtown West, 0.9 km from Enterprise Center

CNY766 total

includes taxes & fees

Jan 22 - Jan 23

Courtyard by Marriott St. Louis Downtown/Convention Center

Downtown St. Louis, 1 km from Enterprise Center

CNY803 total

includes taxes & fees

Jan 25 - Jan 26

Pear Tree Inn St. Louis Convention Center

Downtown St. Louis, 1.3 km from Enterprise Center

CNY766 total

includes taxes & fees

Jan 22 - Jan 23

Hilton Pennywell St. Louis at the Arch

Downtown St. Louis, 1.2 km from Enterprise Center

CNY881 total

includes taxes & fees

Jan 24 - Jan 25

Hotel Saint Louis, Autograph Collection

Downtown St. Louis, 1 km from Enterprise Center

CNY1,210 total

includes taxes & fees

Jan 23 - Jan 24

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Downtown St. Louis, 1 km from Enterprise Center

CNY724 total

includes taxes & fees

Jan 25 - Jan 26

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

2.8 km from Enterprise Center

CNY980 total

includes taxes & fees

Jan 22 - Jan 23

Indoor pool, open 6:00 AM to 10:00 PM, sun loungers

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Downtown St. Louis, 1.4 km from Enterprise Center

CNY795 total

includes taxes & fees

Jan 24 - Jan 25

Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis, 1.2 km from Enterprise Center

CNY911 total

includes taxes & fees

Jan 24 - Jan 25

Courtyard by Marriott St. Louis Downtown West

Downtown West, 1.1 km from Enterprise Center

CNY894 total

includes taxes & fees

Jan 25 - Jan 26

Missouri Athletic Club

Downtown St. Louis, 1.4 km from Enterprise Center

CNY1,418 total

includes taxes & fees

Jan 19 - Jan 20

Premium bedding, down comforters, pillowtop beds, in-room safe

The Westin St. Louis

Downtown St. Louis, 0.8 km from Enterprise Center

CNY1,171 total

includes taxes & fees

Jan 23 - Jan 24

Hyatt Regency St. Louis at The Arch

Downtown St. Louis, 1.3 km from Enterprise Center

CNY1,028 total

includes taxes & fees

Jan 19 - Jan 20

View all properties

Other landmarks near Enterprise Center

St. Louis City Hall

If you're planning a bit of sightseeing head to St. Louis City Hall— just one of the monuments in Downtown West. Why not live the cultural experience and visit the museums and art galleries in the area— your sightseeing tour starts here. St. Louis has other landmarks you might want to visit such as St. Louis Union Station.

See properties

Citygarden

If you like quiet time surrounded by flowers and greenery, hang out at Citygarden in Downtown West. Our travelers also like the art galleries and museums in the area. Want to stretch your legs some more? Head to Lucas Garden Park and Citygarden Sculpture Park, both a short walk away.

See properties

St. Louis Aquarium at Union Station

It's feeding time at the zoo! If you want to be reminded of some of the great animals our world is home to, you might want to pay a trip to St. Louis Aquarium at Union Station, located 0.5 mi (0.8 km) from central St. Louis. If you have fun at St. Louis Aquarium at Union Station, you'll love St. Louis Union Station Mini Golf and The St. Louis Wheel, both a short walk away.

See properties

Frequently asked questions

What are the best hotels near Enterprise Center?

Guests love staying at 21C Museum Hotel St Louis, which is a hotel near Enterprise Center.
OYO Hotel St. Louis Downtown City Center MO is another well-reviewed hotel and is just steps away.
The area has plenty to choose from with 2,097 lodging options including hotels and vacation rentals.

How much does it cost to stay in a hotel near Enterprise Center?

You can find a variety of room prices on Hotels.com depending on where you plan to go and when. To see the lowest rates available, filter by your preferred criteria and sort by price.

Search for the lowest price per night from CNY724

What cheap hotels are close to Enterprise Center?

For a wallet-friendly hotel close to Enterprise Center, Drury Plaza Hotel St. Louis at the Arch is a good option and offers a free buffet breakfast, a free daily manager's reception, and free in-room WiFi.
A second low-cost choice is Casino Queen Hotel, which is a short drive away.

Can I find hotels close to Enterprise Center that are fully refundable?

Yes, many hotels offer refundable room reservations if you cancel prior to the cancellation deadline. Find refundable rates using the "Fully refundable" filter when you search for hotels.

A couple of highly rated hotels close to Enterprise Center that offer these rates are Four Seasons Hotel St Louis and 21C Museum Hotel St Louis.

What are the best romantic hotels near Enterprise Center?

For travelers looking for a romantic stay, The Westin St. Louis offers a restaurant and a bar/lounge. It's steps from Enterprise Center.
Hotel Saint Louis, Autograph Collection is another great choice, and it's just steps away.

What are the best hotels close to Enterprise Center with free breakfast?

Begin your day with a free buffet breakfast at Drury Inn & Suites St. Louis Union Station, which is steps from Enterprise Center.
Home2 Suites by Hilton St. Louis Downtown is also a recommended place to stay with a free buffet breakfast, and it's located just steps away.

Which hotels near Enterprise Center have rooms with great views?

Travelers can enjoy rooms with city views at 21C Museum Hotel St Louis, which is steps from Enterprise Center.
Another great choice nearby is OYO Hotel St. Louis Downtown City Center MO, which has rooms with ocean or city views.

What are the best family hotels close to Enterprise Center?

The entire family will enjoy a stay at OYO Hotel St. Louis Downtown City Center MO which offers free cribs. Enterprise Center is just steps away.
Another great option for your family's trip is The Westin St. Louis.

What are the best luxury hotels near Enterprise Center?

Indulge yourself when you stay at 21C Museum Hotel St Louis, which is steps from Enterprise Center and offers an indoor pool, massages, and a steam room.
Another upscale property is The Last Hotel, which is just steps away.

What are the best hotels near Enterprise Center with free parking?

Travelers looking to drive and park with ease should consider a stay at Pear Tree Inn St. Louis Near Union Station, which offers free parking. You'll be steps from Enterprise Center.
Another property that offers free parking is Comfort Inn & Suites Saint Louis Lafayette Square, which is a short drive away.

What are the best hotels near Enterprise Center with a pool?

If swimming is at the top of your list, 21C Museum Hotel St Louis has an indoor pool. Enterprise Center is steps from the hotel.
Another great choice for a hotel with a pool is The Last Hotel.

What cheap motels can I book close to Enterprise Center?

To stay economically near Enterprise Center, you can book First Western Inn, which offers a hot tub and parking.
Another inexpensive motel nearby to consider is Indian Mound Motel.

What are the best things to see and do around my hotel near Enterprise Center?

On top of your itinerary might be an event or game at Enterprise Center, though you may also want to see local attractions like Gateway Arch, St. Louis Zoo, and Dome at America's Center.
Busch Stadium, City Museum, and Forest Park are other places to visit in the area.

What are the best pet-friendly hotels close to Enterprise Center?

Bring your cherished pet with you to 21C Museum Hotel St Louis, which is steps from Enterprise Center.
Another pet-friendly spot is OYO Hotel St. Louis Downtown City Center MO.

Keep exploring

Lodging

Hotels near Enterprise Center St. Louis

Room 1

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay near Enterprise Center?

Drury Plaza Hotel St. Louis at the Arch

Drury Inn & Suites St. Louis Union Station

Four Seasons Hotel St Louis

Fairfield Inn & Suites by Marriott St. Louis Downtown

Live by Loews - St.Louis

Grand Center Inn

21C Museum Hotel St Louis

Pear Tree Inn St. Louis Near Union Station

Courtyard by Marriott St. Louis Downtown/Convention Center

Pear Tree Inn St. Louis Convention Center

Hilton Pennywell St. Louis at the Arch

Hotel Saint Louis, Autograph Collection

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Embassy Suites by Hilton St. Louis Downtown

Courtyard by Marriott St. Louis Downtown West

Missouri Athletic Club

The Westin St. Louis

Hyatt Regency St. Louis at The Arch

Other landmarks near Enterprise Center

St. Louis City Hall

Citygarden

Central Public Library

Peabody Opera House

Soldiers Memorial Museum

Centenary United Methodist Church

St. Louis Aquarium at Union Station

Whispering Arch at Union Station

Frequently asked questions

Keep exploring