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Hotels in Isla Santa María
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Finch Bay Galapagos Hotel
Finch Bay Galapagos Hotel
4.5 star property
Puerto Ayora
9.2 out of 10, Wonderful, (88)
9.2/10
Wonderful
(88)
- Luxury beachfront hotel with direct snorkeling access in scenic Puerto Ayora.
The price is CNY3,950
CNY3,950
CNY4,356 total
Jan 20 - Jan 21, 2026
Angermeyer Waterfront Inn
Angermeyer Waterfront Inn
3.5 star property
Puerto Ayora
9.4 out of 10, Exceptional, (125)
9.4/10
Exceptional
(125)
The price is CNY1,923
CNY1,923
CNY2,115 total
Jan 10 - Jan 11, 2026
Palo Santo Galapagos Hotel
Palo Santo Galapagos Hotel
3.0 star property
Puerto Ayora
8.6 out of 10, Excellent, (17)
8.6/10
Excellent
(17)
The price is CNY1,513
CNY1,513
CNY1,665 total
Jan 4 - Jan 5, 2026
Posada del Mar
Posada del Mar
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (213)
9.8/10
Exceptional
(213)
- Discover a hotel steps from Galápagos National Park with exceptional staff service.
The price is CNY574
CNY574
CNY574 total
Dec 28 - Dec 29
Casa del Lago Lodging House
Casa del Lago Lodging House
2.0 star property
Puerto Ayora
7.8 out of 10, Good, (13)
7.8/10
Good
(13)
- Relax in nature's paradise near Galápagos National Park and hiking trails.
The price is CNY422
CNY422
CNY473 total
Jan 3 - Jan 4, 2026
Hotel Ninfa
Hotel Ninfa
3.5 star property
Puerto Ayora
8.4 out of 10, Very Good, (218)
8.4/10
Very Good
(218)
- Unwind near Galápagos National Park with easy access to natural wonders.
Galapagos Chalet
Galapagos Chalet
2.5 star property
Puerto Ayora
4.0 out of 10, (1)
4.0/10
(1)
- Serene beach guesthouse steps from Galápagos National Park and wildlife adventures.
Hostal Sir Francis Drake
Hostal Sir Francis Drake
2.5 star property
Puerto Ayora
7.4 out of 10, Good, (73)
7.4/10
Good
(73)
- Get close to nature in Puerto Ayora with convenient access to Galápagos National Park.
The price is CNY490
CNY490
CNY490 total
Jan 4 - Jan 5, 2026
El Barranco Galapagos
El Barranco Galapagos
2.5 star property
Puerto Ayora
9.6 out of 10, Exceptional, (28)
9.6/10
Exceptional
(28)
- A serene retreat near Galapagos National Park with a refreshing pool and bar.
The price is CNY1,348
CNY1,348
CNY1,348 total
Jan 10 - Jan 11, 2026
Capitan Max B&B
Capitan Max B&B
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (198)
9.8/10
Exceptional
(198)
- Serene B&B minutes from Galápagos National Park for nature enthusiasts.
Ikala Galapagos Hotel
Ikala Galapagos Hotel
4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (126)
9.6/10
Exceptional
(126)
- Boutique retreat with terrace views, minutes from Galápagos National Park.
The price is CNY1,718
CNY1,718
CNY1,890 total
Dec 28 - Dec 29
Hotel Red Booby
Hotel Red Booby
3.0 star property
Puerto Ayora
7.2 out of 10, Good, (20)
7.2/10
Good
(20)
- Tropical retreat near Galápagos National Park with refreshing outdoor pool.
The price is CNY701
CNY701
CNY701 total
Dec 30 - Dec 31
Hotel Flamingo
Hotel Flamingo
3.5 star property
Puerto Ayora
8.8 out of 10, Excellent, (112)
8.8/10
Excellent
(112)
- Experience Galapagos wildlife steps from your door at this tranquil waterfront retreat.
Hostal Costa del Pacifico
Hostal Costa del Pacifico
2.5 star property
Puerto Ayora
7.4 out of 10, Good, (22)
7.4/10
Good
(22)
- Experience Galápagos National Park just steps away from this cozy Puerto Ayora hostal.
The price is CNY433
CNY433
CNY433 total
Jan 2 - Jan 3, 2026
Hostal Miconia
Hostal Miconia
2.5 star property
Puerto Ayora
6.0 out of 10, (40)
6.0/10
(40)
Grand Hotel Leon Marino Galapagos
Grand Hotel Leon Marino Galapagos
3.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (13)
8.8/10
Excellent
(13)
- Modern retreat next to Galápagos National Park with outdoor pool and daily service.
The price is CNY647
CNY647
CNY647 total
Jan 3 - Jan 4, 2026
BAY VIEW HOUSE
BAY VIEW HOUSE
3.5 star property
Puerto Ayora
10.0 out of 10, Exceptional, (4)
10/10
Exceptional
(4)
- Serene island getaway steps from Galápagos National Park with spa indulgences.
The price is CNY1,580
CNY1,580
CNY1,580 total
Dec 28 - Dec 29
Galapagos Dreams
Galapagos Dreams
3.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (124)
8.8/10
Excellent
(124)
- Lush island escape in Puerto Ayora near Galápagos National Park and local piers.
The price is CNY542
CNY542
CNY596 total
Dec 28 - Dec 29
Hotel Santa Fe
Hotel Santa Fe
4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (14)
9.6/10
Exceptional
(14)
- Serene retreat with scenic pool and free bikes near Galápagos National Park.
The price is CNY1,191
CNY1,191
CNY1,310 total
Dec 31 - Jan 1, 2026
Hostal North Seymour
Hostal North Seymour
3.0 star property
Puerto Ayora
8.6 out of 10, Excellent, (145)
8.6/10
Excellent
(145)
- Get close to nature with a cozy B&B just steps from Galápagos National Park.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Budget hotels in Isla Santa María and vicinity
8.0 out of 10, Very Good, (2)
8.0/10
Very Good
(2)
The price is CNY357
CNY357
CNY357 total
Jan 4 - Jan 5, 2026
9.6 out of 10, Exceptional, (4)
9.6/10
Exceptional
(4)
The price is CNY158
CNY158
CNY316 total
Jan 12 - Jan 13, 2026
7.4 out of 10, Good, (80)
7.4/10
Good
(80)
7.4 out of 10, Good, (73)
7.4/10
Good
(73)
The price is CNY490
CNY490
CNY490 total
Jan 4 - Jan 5, 2026
9.0 out of 10, Wonderful, (99)
9.0/10
Wonderful
(99)
8.8 out of 10, Excellent, (6)
8.8/10
Excellent
(6)
The price is CNY511
CNY511
CNY511 total
Jan 1 - Jan 2, 2026
8.6 out of 10, Excellent, (145)
8.6/10
Excellent
(145)
8.4 out of 10, Very Good, (44)
8.4/10
Very Good
(44)
The price is CNY599
CNY599
CNY599 total
Jan 10 - Jan 11, 2026
9.4 out of 10, Exceptional, (6)
9.4/10
Exceptional
(6)
The price is CNY410
CNY410
CNY410 total
Dec 28 - Dec 29
7.6 out of 10, Good, (121)
7.6/10
Good
(121)
8.8 out of 10, Excellent, (124)
8.8/10
Excellent
(124)
The price is CNY542
CNY542
CNY596 total
Dec 28 - Dec 29
8.8 out of 10, Excellent, (176)
8.8/10
Excellent
(176)
9.2 out of 10, Wonderful, (23)
9.2/10
Wonderful
(23)
The price is CNY701
CNY701
CNY701 total
Jan 5 - Jan 6, 2026
8.8 out of 10, Excellent, (41)
8.8/10
Excellent
(41)
The price is CNY425
CNY425
CNY678 total
Jan 22 - Jan 23, 2026
7.4 out of 10, Good, (22)
7.4/10
Good
(22)
The price is CNY433
CNY433
CNY433 total
Jan 2 - Jan 3, 2026
8.4 out of 10, Very Good, (46)
8.4/10
Very Good
(46)
The price is CNY441
CNY441
CNY441 total
Jan 3 - Jan 4, 2026
7.6 out of 10, Good, (28)
7.6/10
Good
(28)
9.0 out of 10, Wonderful, (160)
9.0/10
Wonderful
(160)
The price is CNY477
CNY477
CNY582 total
Dec 28 - Dec 29
9.8 out of 10, Exceptional, (213)
9.8/10
Exceptional
(213)
The price is CNY574
CNY574
CNY574 total
Dec 28 - Dec 29
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Isla Santa María
Family friendly
Ocean view
Top landmarks in Isla Santa María
Learn more about Isla Santa María
Isla Santa María is well-known for its attractions such as Galápagos National Park and Post Office Bay.
Photo by Mark Rentz
Open Photo by Mark Rentz
Check out reviews of Isla Santa María hotels guests love
Acacia Galapagos Boutique Hotel
10/10 Excellent
"We had a great stay at Acacia. The location was very central and walkable to shops, dinner, the Charles Darwin Center, and a couple of beaches. The rooms were spacious and spotlessly clean. And the staff was very friendly and helpful, plus a delicious fresh breakfast daily.
So glad we planned a couple of days in Puerto Ayora - there are sea lions, tortoises, and marine iguanas all over the place and we spent a lovely day at Tortuga Bay (thanks to recommendation from Acacia staff). Wish we had planned more time there. "
Hotel el descanso del Guia
10/10 Excellent
"Pool needs a ladder on the deep side"
Hotel Fiesta
10/10 Excellent
"Staff was efficient room was clean "
Blu Galapagos Sustainable Waterfront Lodge
10/10 Excellent
"Beautiful property "
Capitan Max B&B
10/10 Excellent
"A great property within walking distance from all the restaurants etc. They have a basic breakfast which does the job. The staff were very friendly and accomodating. They even allowed us to get into the room very early after our ferry arriving into Santa Cruz. "
El Barranco Galapagos
10/10 Excellent
"Incredible place to book your stay in Santa Cruz. Excelent service, rooms and personel. "
Maidith Galapagos Inn
10/10 Excellent
"This was a great stay! The hotel is so cute and the staff is top notch! The rooms were spacious, had plenty of shelving, and the bed was comfortable. The hotel is convenient, located near stores, Darwin Ave, restaurants, and bars. It is about a 10 minute walk to the pier, but they will coordinate taxis if you need it. They give you a discount to a local tour agency and restaurant. The staff is very helpful and accommodating. I skipped breakfast and told them I was going to Isabela Island and they made a to-go bag for lunch for me. Highly recommend this place!"
Hotel Palace Galapagos
10/10 Excellent
"Absolutely happy with everything!!!! My room was cleaned before I back from my day out!!! Great service! Recommend to everyone!!! Close to everything !! Loved it "
Hotel Cucuve
10/10 Excellent
"Best place we stayed at in Ecuador. Clean, friendly and affordable. "
Frequently asked questions
How much does a hotel room cost in Isla Santa María?
You can choose a great hotel in Isla Santa María from CNY567 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Isla Santa María that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.
How can I find deals and earn rewards at Isla Santa María hotels?
Discover great deals on Isla Santa María hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Isla Santa María hotels.
Can I book Isla Santa María hotels with free cancellation?
In order to book a refundable Isla Santa María hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
Can I book refundable hotels in Isla Santa María?
If you're looking for the flexibility to change your plans to Isla Santa María, most properties provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Isla Santa María be like during my trip?
With an average temperature of 72°F, Isla Santa María is a great place if you want to enjoy the sunshine year all year long.
Why should I book my Isla Santa María hotel through Hotels.com?
There are plenty of reasons to book your Isla Santa María travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.