Hotels in Rochester
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La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic Scleanliness Convenient location near Mayo Clinic with free daily breakfast and on-site fitness.

Econo Lodge Mayo Clinic Area
Econo Lodge Mayo Clinic Areacleanliness Restful retreat near Mayo Clinic with 24-hour fitness center and complimentary perks.

Spark by Hilton Rochester South
Spark by Hilton Rochester Southcleanliness Cozy lodging near Mayo Clinic with complimentary breakfast and indoor pool access.

Country Inn & Suites Rochester South Mayo Clinic
Country Inn & Suites Rochester South Mayo Cliniccleanliness A peaceful Mayo Clinic escape with complimentary hot breakfast and tranquil pool area.

Days Inn by Wyndham Austin
Days Inn by Wyndham Austincleanliness Stay close to downtown Austin with free breakfast, Wi-Fi, and parking on-site.

Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHGcleanliness Modern rooms near Mayo Clinic with indoor pool and free hot breakfast daily.

Cobblestone Hotel & Suites - Austin
Cobblestone Hotel & Suites - Austincleanliness Experience the charm of Austin with modern amenities and a relaxing indoor pool.

Hampton Inn Rochester-South
Hampton Inn Rochester-Southcleanliness Peaceful hotel near Mayo Clinic with indoor pool and daily complimentary breakfast.

Sleep Inn & Suites West-Near Medical Center
Sleep Inn & Suites West-Near Medical Centercleanliness Convenient hotel near Mayo Clinic with indoor pool and complimentary perks.

Comfort Inn & Suites West - Medical Center
Comfort Inn & Suites West - Medical Centercleanliness Stay minutes from Mayo Clinic with indoor pool and fitness center access.

Quality Inn & Suites Mayo Clinic Area
Quality Inn & Suites Mayo Clinic Areacleanliness Quiet refuge in Rochester's medical district with free hot breakfast daily.

Comfort Inn & Suites Rochester South Mayo Clinic
Comfort Inn & Suites Rochester South Mayo Cliniccleanliness Stay minutes from Rochester airport with a rejuvenating pool and hot tub.

Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Areacleanliness Serene stay near Mayo Clinic with easy access to local dining and shopping options.

Home2 Suites by Hilton Rochester Mayo Clinic Area
Home2 Suites by Hilton Rochester Mayo Clinic Areacleanliness Convenient stay minutes from Mayo Clinic with indoor pools and free breakfast.

AmericInn by Wyndham Austin
AmericInn by Wyndham Austincleanliness Unwind in a peaceful Austin retreat with a relaxing indoor pool and hot tub.

Americas Best Value Inn & Suites Spring Valley
Americas Best Value Inn & Suites Spring Valleycleanliness Affordable comfort near Rochester with fitness center and free breakfast perks.

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHGcleanliness Enjoy a tranquil stay near Mayo Clinic with indoor pool and complimentary perks.

Hampton Inn & Suites Rochester-North
Hampton Inn & Suites Rochester-Northcleanliness Modern Rochester hotel with Mayo Clinic access and revitalizing pool amenities.

Stone Mill Hotel & Suites
Stone Mill Hotel & Suitescleanliness Experience the serenity of countryside living at this golf-adjacent retreat in Lanesboro.

Super 8 by Wyndham Rochester Mayo Clinic Area
Super 8 by Wyndham Rochester Mayo Clinic Areacleanliness Peaceful retreat near Mayo Clinic with free WiFi, parking, and breakfast daily.
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La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Broadway Plaza, Trademark Collection by Wyndham
Broadway Plaza, Trademark Collection by WyndhamCheck out hotels with a pool in Rochester

Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHGYou may also like pet-friendly hotels in Rochester

You can also stay at hotels with a hot tub in Rochester

Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHGGo beyond your typical stay in Rochester
Top neighborhoods in Rochester

Downtown Rochester
Downtown Rochester revolves around Mayo Clinic's impressive medical campus where modern buildings and the historic Plummer Building create a distinctive skyline. The peaceful Peace Plaza offers a quiet spot with fountains and sculptures between appointments. Rochester Civic Theater and Mayo Civic Center provide cultural experiences, while nearby Silver Lake Park lets visitors unwind with scenic walking paths. Getting around is a breeze with the Mayo shuttle system connecting medical facilities and abundant public transit options. Hotels cater specifically to medical visitors with extended-stay amenities and clinic shuttles. Restaurants offer healthy dining choices with extended hours, understanding that healing happens on its own schedule.

Kutzky Park
Kutzky Park offers a charming retreat with tree-lined streets and well-preserved early 20th-century homes. Wander through the neighborhood's namesake park where mature oaks and maples shade winding paths and playgrounds. Architecture enthusiasts will appreciate the Craftsman and Colonial Revival styles that showcase Rochester's historical development. This quiet residential haven provides a genuine local experience away from tourist crowds. While dining options are limited within the neighborhood, downtown Rochester's restaurants are just a short drive away. Visitors typically stay in private home rentals or intimate bed-and-breakfasts with personalized local recommendations.

Historic Southwest
Historic Southwest offers a window into Rochester's medical heritage through grand century-old homes once built for Mayo Clinic physicians. Take peaceful strolls along tree-canopied streets showcasing Colonial Revival, Tudor, and Prairie architectural styles. The neighborhood's elegant brick facades, wraparound porches, and manicured gardens create a living museum atmosphere perfect for architecture enthusiasts and photographers. Accommodation options include upscale bed & breakfasts in converted physician mansions with period furnishings and personalized service. While dining and shopping require a quick 10-minute drive to downtown Rochester, the quiet residential atmosphere provides a welcome retreat from urban bustle.
East Side Pioneers
East Side Pioneers is a peaceful suburban retreat away from Rochester's downtown buzz. Visit the Rochester Art Center for local creativity or catch a performance at the Rochester Civic Theater. The neighborhood borders Mayo Park and Silver Lake Park, perfect spots for morning walks or afternoon picnics when you need a break from medical appointments or sightseeing. This budget-friendly area offers affordable extended-stay hotels and vacation rentals that won't break the bank. Most dining requires a quick 10-15 minute drive to downtown, where you'll find diverse restaurant options. The wide sidewalks and quiet streets make neighborhood exploration easy, even without a car.

Slatterly Park
Slatterly Park neighborhood invites visitors into authentic Rochester life away from tourist crowds. Tree-lined streets showcase charming Craftsman bungalows and Colonial Revivals, highlighting the city's architectural heritage. The namesake park provides serene green space where locals walk dogs and children play. Just beyond the quiet neighborhood borders, Rochester Art Center and Soldiers Field Veterans Memorial await exploration. This residential area is best navigated by car, though pleasant sidewalks under mature elm and oak trees make for delightful strolls. Downtown Rochester's dining and shopping options are just a short drive away. While accommodations within Slatterly Park are limited, its peaceful atmosphere makes it worth visiting regardless of where travelers choose to stay.
Top landmarks in Rochester
Rochester and related destinations
Beyond the world-famous Mayo Clinic, discover a city with surprising depth. The Plummer Building's Gothic tower stands as an architectural masterpiece worth admiring even if not seeking medical care. Kayak the gentle Zumbro River for a different perspective of downtown, or catch a performance at the Rochester Civic Theater where productions rival those in much larger cities. The Mayowood Mansion offers a glimpse into the Mayo family's private world through guided tours of their historic estate. Art enthusiasts shouldn't miss the Rochester Art Center's contemporary exhibitions overlooking the river. After cultural pursuits, join locals at a Rochester Honkers baseball game where small-town America meets big-league enthusiasm.

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Hyatt House Rochester/Mayo Clinic Area
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