Hotels in Mesilla

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Mesilla?

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
3.0 star property
Las Cruces
8.2 out of 10, Very Good, (2,343 reviews)
  • cleanliness
    Wake up to majestic mountain views at this relaxing Las Cruces retreat.
The price is CNY407
CNY479 total
includes taxes & fees
Jan 22 - Jan 23
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Hampton Inn & Suites Las Cruces I-10
Hampton Inn & Suites Las Cruces I-10
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Take a dip in the indoor pool or hit the fitness center after exploring Las Cruces.
The price is CNY622
CNY723 total
includes taxes & fees
Feb 1 - Feb 2
Hampton Inn & Suites Las Cruces I-10
Drury Inn & Suites Las Cruces
Drury Inn & Suites Las Cruces
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    Stay minutes from Luna Rossa Winery at this Las Cruces hotel with indoor pool.
The price is CNY655
CNY760 total
includes taxes & fees
Jan 25 - Jan 26
Drury Inn & Suites Las Cruces
Days Inn by Wyndham Las Cruces
Days Inn by Wyndham Las Cruces
2.5 star property
Las Cruces
8.2 out of 10, Very Good, (1,328 reviews)
The price is CNY337
CNY400 total
includes taxes & fees
Jan 25 - Jan 26
Days Inn by Wyndham Las Cruces
Comfort Inn & Suites Las Cruces Mesilla
Comfort Inn & Suites Las Cruces Mesilla
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Relax in this Las Cruces hotel near wineries with indoor pool and hot tub.
The price is CNY683
CNY792 total
includes taxes & fees
Jan 25 - Jan 26
Comfort Inn & Suites Las Cruces Mesilla
Best Western Mission Inn
Best Western Mission Inn
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,218 reviews)
  • cleanliness
    Quiet rooms near New Mexico State University with a helpful staff and tasty cafe.
The price is CNY533
CNY622 total
includes taxes & fees
Jan 25 - Jan 26
Best Western Mission Inn
Ramada Hotel & Conference Center by Wyndham Las Cruces
Ramada Hotel & Conference Center by Wyndham Las Cruces
3.0 star property
Las Cruces
8.0 out of 10, Very Good, (1,007 reviews)
  • cleanliness
    Tranquil Las Cruces haven with courtyard and pool near Pan American Center.
The price is CNY551
CNY641 total
includes taxes & fees
Jan 27 - Jan 28
Ramada Hotel & Conference Center by Wyndham Las Cruces
Springhill Suites By Marriott Las Cruces
Springhill Suites By Marriott Las Cruces
3.0 star property
Las Cruces
8.4 out of 10, Very Good, (974 reviews)
  • cleanliness
    Enjoy comfort in Las Cruces near restaurants, wine destinations, and outdoor fun.
The price is CNY648
CNY752 total
includes taxes & fees
Jan 26 - Jan 27
Springhill Suites By Marriott Las Cruces
Courtyard by Marriott Las Cruces at NMSU
Courtyard by Marriott Las Cruces at NMSU
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (518 reviews)
  • cleanliness
    Convenient campus locale with heated pool for year-round southwestern relaxation.
The price is CNY912
CNY1,052 total
includes taxes & fees
Feb 7 - Feb 8
Courtyard by Marriott Las Cruces at NMSU
Quality Inn & Suites Las Cruces - University Area
Quality Inn & Suites Las Cruces - University Area
2.5 star property
Las Cruces
7.0 out of 10, Good, (1,001 reviews)
  • cleanliness
    Stay comfortably near New Mexico State University at this quiet, well-maintained hotel.
The price is CNY366
CNY433 total
includes taxes & fees
Feb 19 - Feb 20
Quality Inn & Suites Las Cruces - University Area
Big Chile Inn & Suites
Big Chile Inn & Suites
2.0 star property
Las Cruces
7.0 out of 10, Good, (53 reviews)
  • cleanliness
    Close to Las Cruces museums with free WiFi and parking near New Mexico State.
The price is CNY503
CNY587 total
includes taxes & fees
Feb 1 - Feb 2
Big Chile Inn & Suites
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
3.0 star property
Las Cruces
5.4 out of 10, (1,002 reviews)
  • cleanliness
    Spacious rooms near Luna Rossa Winery with free parking and WiFi.
The price is CNY290
CNY346 total
includes taxes & fees
Jan 25 - Jan 26
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
Econo Lodge Las Cruces University Area
Econo Lodge Las Cruces University Area
2.0 star property
Las Cruces
7.2 out of 10, Good, (642 reviews)
  • cleanliness
    Steps from New Mexico State University, this hotel serves up free breakfast daily.
The price is CNY388
CNY480 total
includes taxes & fees
Feb 19 - Feb 20
Econo Lodge Las Cruces University Area
Hilton Garden Inn Las Cruces
Hilton Garden Inn Las Cruces
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (1,006 reviews)
  • cleanliness
    Peaceful Las Cruces hotel with on-site dining and fitness options near Pan American Center.
The price is CNY628
CNY730 total
includes taxes & fees
Feb 1 - Feb 2
Hilton Garden Inn Las Cruces
Las Cruces Home w/ Fenced Yard: Recently Remodeled
Las Cruces Home w/ Fenced Yard: Recently Remodeled
3.0 star property
Las Cruces
  • cleanliness
    Enjoy a charming cottage with a patio and kitchen in the heart of Las Cruces.
The price is CNY724
CNY1,828 total
includes taxes & fees
Feb 1 - Feb 2
Las Cruces Home w/ Fenced Yard: Recently Remodeled
Comfort Suites University Las Cruces
Comfort Suites University Las Cruces
2.5 star property
Las Cruces
8.0 out of 10, Very Good, (1,006 reviews)
  • cleanliness
    Peaceful golf-adjacent hotel provides serene atmosphere near Pan American Center.
The price is CNY556
CNY648 total
includes taxes & fees
Feb 1 - Feb 2
Comfort Suites University Las Cruces
Hampton Inn & Suites Las Cruces I-25
Hampton Inn & Suites Las Cruces I-25
2.5 star property
Las Cruces
8.4 out of 10, Very Good, (1,000 reviews)
The price is CNY623
CNY724 total
includes taxes & fees
Feb 1 - Feb 2
Hampton Inn & Suites Las Cruces I-25
Desert Haven Cozy 2-Bedroom Mobile Home Near NMSU 2 Home
Desert Haven Cozy 2-Bedroom Mobile Home Near NMSU 2 Home
3.0 star property
Las Cruces
  • cleanliness
    Relax in a cozy Las Cruces home near American Southwest Theater and hiking trails.
The price is CNY911
CNY2,786 total
includes taxes & fees
Jan 26 - Jan 27
Desert Haven Cozy 2-Bedroom Mobile Home Near NMSU 2 Home
Motel 9 Las Cruces
Motel 9 Las Cruces
2.5 star property
Las Cruces
6.2 out of 10, (242 reviews)
  • cleanliness
    Affordable university lodgings with complimentary WiFi and parking nearby.
The price is CNY276
CNY330 total
includes taxes & fees
Jan 22 - Jan 23
Motel 9 Las Cruces
Hotel Encanto de Las Cruces
Hotel Encanto de Las Cruces
3.5 star property
Las Cruces
9.0 out of 10, Wonderful, (1,623 reviews)
  • cleanliness
    Serene mountain views from a Mexican-inspired hotel with poolside comfort.
The price is CNY997
CNY1,336 total
includes taxes & fees
Jan 22 - Jan 23
Hotel Encanto de Las Cruces
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Mesilla

Learn more about Mesilla

Centuries-old adobe buildings frame the historic plaza, where the Confederate Territory of Arizona once claimed its brief capital. Duck into La Posta de Mesilla, a former stagecoach stop now serving chile rellenos that locals defend with patriotic fervor. The Fountain Theatre screens independent films in what might be the oldest movie house in the Southwest. Browse galleries where artists capture desert light in ways that make you understand why Georgia O'Keeffe never left. The Mesilla Plaza, a National Historic Landmark, hosts festivals where the smell of roasting green chiles mingles with mariachi music. Las Cruces sits just next door with its Museum of Nature & Science when you've had your fill of history.

Red chile doorway Mesilla NM

Check out reviews of Mesilla hotels guests love

Frequently asked questions

How much does a hotel room cost in Mesilla?
You can discover great hotels in Mesilla from CNY330 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Mesilla that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.
How can I find deals and earn rewards at Mesilla hotels?
Discover great deals on Mesilla hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Mesilla hotels.
Can I book Mesilla hotels with free cancellation?
In order to book a refundable Mesilla hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are some popular hotels in central Mesilla?
If you're looking for hotels in central Mesilla, check out La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Drury Inn & Suites Las Cruces. Travelers love La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain for its location, as well as the outdoor pool, free continental breakfast and free parking this hotel offers. Drury Inn & Suites Las Cruces is another popular central hotel with an indoor pool, a hot tub and a free buffet breakfast. When you stay at one of these central hotels, you'll be in easy reach of top sights including New Mexico State University. Picacho Hills is a central neighborhood for your Mesilla vacation.
What hotels do travelers like in Mesilla?
Can I book a refundable hotel in Mesilla?
If you want the flexibility to change your travel plans to Mesilla, most accommodations offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Mesilla if I want a vacation rental instead of a traditional hotel?
If you're looking for a good alternative to a hotel, review our selection of 9 vacation homes.
What will the weather in Mesilla be like during my trip?
The warmest months in Mesilla are usually June and July with an average temp of 82°F. January and December are the chilliest months when the average temp is 48°F. The rainiest months are August and September.
Why should I book my Mesilla accommodation with Hotels.com?
There are plenty of reasons to book your Mesilla travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.