Hotels in Santee

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Check prices for these dates

Tonight
Dec 20 - Dec 21
Tomorrow
Dec 21 - Dec 22
Next weekend
Dec 26 - Dec 28
In two weeks
Jan 2 - Jan 4

Where to stay in Santee?

Property amenity
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
2.5 star property
9.8 out of 10, Exceptional, (1002)
The price is CNY852
CNY946 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Fairfield Inn & Suites by Marriott Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Budget hotels in Santee and vicinity

Front of property
Peach Tree Inn

Peach Tree Inn

Peach Tree Inn
2.5 star property
St. George
7.2 out of 10, Good, (140)
Peach Tree Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out pet-friendly hotels in Santee

Lobby
Tru By Hilton Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (643)
The price is CNY746
CNY828 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Tru By Hilton Santee
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You may also like hotels with pools in Santee

Lobby
Tru By Hilton Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (643)
The price is CNY746
CNY828 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Tru By Hilton Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit Santee?

Our prices for hotels in Santee are cheapest in February
Price trends for hotels in Santee
Pricing is based on two traveler single night rates
View properties in December
Currently viewing crowd sizes and weather for December.
Typical weather for Santee
December
High crowds
High 15°C / low 7°C. Sunny most days.
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15°
weather_sun
December, High crowds, average high temperature 15 degrees Celsius, average low temperature 7 degrees Celsius. Sunny most days.
7°
13°
weather_sun
January, Low crowds, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Sunny most days.
4°
16°
weather_sun
February, Low crowds, average high temperature 16 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
6°
19°
weather_sun
March, High crowds, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
24°
weather_sun
April, Moderate crowds, average high temperature 24 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
28°
weather_sun
May, Moderate crowds, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
31°
weather_sun
June, Moderate crowds, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
33°
weather_sun
July, Moderate crowds, average high temperature 33 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
32°
weather_sun
August, Low crowds, average high temperature 32 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
29°
weather_sun
September, Low crowds, average high temperature 29 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
24°
weather_sun
October, High crowds, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
19°
weather_sun
November, High crowds, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
Monthly weather averages (˚C)

Top landmarks in Santee

Santee State Park

4.0/5 (112 reviews)
Santee State Park is 2.7 mi (4.4 km) from central Santee, why not stop by during your stay.
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Santee Cooper Country Club

3.9/5 (47 reviews)
You might want to play some rounds at Santee Cooper Country Club, located 0.6 mi (1 km) from central Santee. If Santee Cooper Country Club doesn't quite scratch your golfing itch, Santee National Golf Club is also nearby.
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Learn more about Santee

Tee off at championship golf courses or cast a line in Lake Marion's fish-rich waters where locals claim the bass practically jump into your boat. The Santee National Wildlife Refuge offers hiking trails where alligators sun themselves with reptilian nonchalance. Interstate 95 crosses the lake on a causeway that provides views worth pulling over for (safely, of course). Santee State Park delivers lakeside tranquility that makes visitors forget their phones exist. This resort town punches well above its weight with dining options that range from fresh-caught catfish to surprisingly sophisticated fare. The recent addition of the Santee Cooper Regional Water System has locals buzzing about growth while still cherishing their small-town atmosphere.

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Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Check out reviews of Santee hotels guests love

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

10/10 Excellent
"Staff was pleasant and helpful with restaurant information, room clean. "
Mark 1-night trip
Posted 5 days ago
Comfort Inn & Suites Santee

Frequently asked questions

How much does a hotel room cost in Santee?
You can find top hotels in Santee from CNY446 with options to suit your budget and needs. Baymont by Wyndham Santee is one low-cost option that's popular with our travelers. If you're looking for an affordable hotel in Santee that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.
How can I find deals and earn rewards at Santee hotels?
Discover great deals on Santee hotel stays with Hotels.com. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Santee hotels.
Can I book Santee hotels with free cancellation?
In order to book a refundable Santee hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are some top pet-friendly hotels in Santee?
Our travelers' top pet-friendly hotels in Santee include:You can also use the "Amenities" filter in your search on Hotels.com and check "Pet friendly" to discover more pet-friendly hotels in Santee.
What are the top Santee hotels with a pool?
For a little extra luxury, discover some of the best Santee hotels with a pool. Holiday Inn Santee by IHG is a great hotel with an indoor pool and a guest rating of 8.2 out of 10. Plus, you can make the most of its restaurant and bar/lounge. To find more stays in Santee with a pool, use the "Amenities" filter on Hotels.com in your search and select "Pool".
What are some of the best Santee hotels with free parking?
If you're exploring by car, finding a great Santee hotel with free parking is a win. Our travelers' favorites include:
What are some popular hotels in central Santee?
If you're looking for hotels in central Santee, check out Holiday Inn Santee by IHG. Travelers love Holiday Inn Santee by IHG for its location, as well as the indoor pool, restaurant and bar/lounge this hotel offers.
What accommodations do travelers like in Santee?
Hampton Inn Santee-I-95, Fairfield Inn & Suites by Marriott Santee and Tru By Hilton Santee are all accommodations that are popular with guests.
Can I book refundable accommodations in Santee?
If you want the flexibility to change your plans to Santee, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where should I stay in Santee if I'm looking for a reasonably priced accommodation?
A few inexpensive options worth considering are Tru By Hilton Santee, Baymont by Wyndham Santee and Hampton Inn Santee-I-95.
Where can I stay in Santee if I want a vacation rental instead of a hotel?
Browse 9 vacation homes on our site. You also might want to book one of 94 condos for your trip.
What will the weather in Santee be like during my vacation?
July and August are typically the warmest months in Santee when the average temp is 79°F. January and February are the coldest months when the average temperature is 52°F. August and July are the months with the most rain.

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