Hotels in Byron

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Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (913 reviews)
  • cleanliness
    Relax in quiet comfort with Mayo Clinic just a 15-minute walk away from this hotel.
The price is CNY530
CNY610 total
includes taxes & fees
Jan 30 - Jan 31
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hampton Inn Rochester-South
Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Peaceful hotel near Mayo Clinic with indoor pool and daily complimentary breakfast.
The price is CNY524
CNY603 total
includes taxes & fees
Feb 6 - Feb 7
Hampton Inn Rochester-South
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.2 out of 10, Good, (1,029 reviews)
  • cleanliness
    Convenient location near Mayo Clinic with free daily breakfast and on-site fitness.
The price is CNY533
CNY614 total
includes taxes & fees
Jan 18 - Jan 19
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester
9.0 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Stay near Mayo Clinic with comfort amenities and complimentary breakfast.
The price is CNY948
CNY1,092 total
includes taxes & fees
Feb 13 - Feb 14
Hyatt House Rochester/Mayo Clinic Area
Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Modern rooms near Mayo Clinic with indoor pool and free hot breakfast daily.
The price is CNY509
CNY586 total
includes taxes & fees
Jan 23 - Jan 24
Holiday Inn Express Rochester South - Mayo Area by IHG
Country Inn & Suites Rochester South Mayo Clinic
Country Inn & Suites Rochester South Mayo Clinic
3.0 star property
Rochester
8.4 out of 10, Very Good, (1,002 reviews)
  • cleanliness
    A peaceful Mayo Clinic escape with complimentary hot breakfast and tranquil pool area.
The price is CNY627
CNY722 total
includes taxes & fees
Jan 25 - Jan 26
Country Inn & Suites Rochester South Mayo Clinic
Hilton Garden Inn Rochester Downtown, MN
Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester
8.8 out of 10, Excellent, (863 reviews)
  • cleanliness
    A welcoming downtown haven near Mayo Clinic with indoor pool and hot tub.
The price is CNY746
CNY858 total
includes taxes & fees
Jan 30 - Jan 31
Hilton Garden Inn Rochester Downtown, MN
Kahler Grand Hotel
Kahler Grand Hotel
3.0 star property
Downtown Rochester
8.4 out of 10, Very Good, (1,855 reviews)
  • cleanliness
    Quiet historic escape with indoor pool, minutes from Mayo Clinic facilities.
Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
Downtown Rochester
8.0 out of 10, Very Good, (1,522 reviews)
  • cleanliness
    Mayo Clinic stay offers quiet retreat with convenient access to medical facilities.
Kahler Inn and Suites - Mayo Clinic Area
Spark by Hilton Rochester South
Spark by Hilton Rochester South
3.0 star property
Rochester
9.2 out of 10, Wonderful, (349 reviews)
  • cleanliness
    Cozy lodging near Mayo Clinic with complimentary breakfast and indoor pool access.
The price is CNY508
CNY585 total
includes taxes & fees
Jan 25 - Jan 26
Spark by Hilton Rochester South
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
Historic Southwest
8.6 out of 10, Excellent, (1,002 reviews)
  • cleanliness
    Peaceful stay within walking distance of Mayo Clinic, featuring a dining tavern.
The price is CNY828
CNY954 total
includes taxes & fees
Jan 18 - Jan 19
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Hampton Inn & Suites Rochester-North
Hampton Inn & Suites Rochester-North
2.5 star property
Rochester
9.2 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Modern Rochester hotel with Mayo Clinic access and revitalizing pool amenities.
The price is CNY623
CNY717 total
includes taxes & fees
Jan 25 - Jan 26
Hampton Inn & Suites Rochester-North
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park
9.2 out of 10, Wonderful, (776 reviews)
The price is CNY655
CNY754 total
includes taxes & fees
Jan 30 - Jan 31
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Comfort Inn & Suites Rochester South Mayo Clinic
Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
Rochester
8.8 out of 10, Excellent, (1,004 reviews)
  • cleanliness
    Stay minutes from Rochester airport with a rejuvenating pool and hot tub.
The price is CNY528
CNY607 total
includes taxes & fees
Feb 15 - Feb 16
Comfort Inn & Suites Rochester South Mayo Clinic
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park
8.8 out of 10, Excellent, (771 reviews)
  • cleanliness
    Enjoy a tranquil stay near Mayo Clinic with indoor pool and complimentary perks.
The price is CNY718
CNY827 total
includes taxes & fees
Feb 1 - Feb 2
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
2.5 star property
Kutzky Park
9.6 out of 10, Exceptional, (684 reviews)
  • cleanliness
    Stay moments from Mayo Clinic with shuttle service at this well-appointed hotel.
The price is CNY683
CNY786 total
includes taxes & fees
Feb 7 - Feb 8
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Econo Lodge Mayo Clinic Area
Econo Lodge Mayo Clinic Area
2.0 star property
Rochester
9.0 out of 10, Wonderful, (918 reviews)
  • cleanliness
    Restful retreat near Mayo Clinic with 24-hour fitness center and complimentary perks.
The price is CNY440
CNY507 total
includes taxes & fees
Jan 31 - Feb 1
Econo Lodge Mayo Clinic Area
EVEN Hotel Rochester - Mayo Clinic Area by IHG
EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (979 reviews)
  • cleanliness
    Located near Mayo Clinic with wellness-focused amenities and an indoor pool.
The price is CNY764
CNY893 total
includes taxes & fees
Jan 18 - Jan 19
EVEN Hotel Rochester - Mayo Clinic Area by IHG
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.2 out of 10, Very Good, (1,177 reviews)
  • cleanliness
    Peaceful retreat near Mayo Clinic with serene atmosphere and indoor pool.
The price is CNY532
CNY612 total
includes taxes & fees
Jan 25 - Jan 26
AmericInn by Wyndham Rochester Near Mayo Clinic
Americas Best Value Inn & Suites Spring Valley
Americas Best Value Inn & Suites Spring Valley
2.0 star property
Spring Valley
8.2 out of 10, Very Good, (435 reviews)
  • cleanliness
    Affordable comfort near Rochester with fitness center and free breakfast perks.
The price is CNY528
CNY582 total
includes taxes & fees
Jan 18 - Jan 19
Americas Best Value Inn & Suites Spring Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a hotel room cost in Byron?
You can find top hotels in Byron from CNY507 with options to suit your budget and needs. To find an affordable hotel in Byron that meets all of your requirements, just apply filters on Hotels.com and sort hotels by "Price: low to high".
How can I find deals and earn rewards at Byron hotels?
Discover great deals on Byron hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. And make sure to check out our last-minute deals on Byron hotels.
Can I book Byron hotels with free cancellation?
To book a refundable Byron hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What hotels do travelers recommend in Byron?
Can I book refundable accommodations in Byron?
If you're looking for the flexibility to change your plans to Byron, most properties provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Byron be like during my vacation?
July and August are typically the warmest months in Byron when the average temp is 67°F. January and February are the coldest months when the average temperature is 21°F. June and May are the months with the most rain.
Why should I book my Byron hotel with Hotels.com?
There are lots of reasons to book your Byron trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.