Hotels in Santa Ana
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Where to stay in Santa Ana?
7.2 out of 10, Good, (15)
7.2/10
Good
(15)
The price is CNY437
CNY437
CNY675 total
includes taxes & fees
Dec 22 - Dec 23
7.6 out of 10, Good, (55)
7.6/10
Good
(55)
The price is CNY179
CNY179
CNY196 total
includes taxes & fees
Jan 2 - Jan 3, 2026
6.6 out of 10, (182)
6.6/10
(182)
6.0 out of 10, (11)
6.0/10
(11)
9.2 out of 10, Wonderful, (55)
9.2/10
Wonderful
(55)
Room-sofa Bed Stay Rooftop Pool & Gym, A
Room-sofa Bed Stay Rooftop Pool & Gym, A2.0 star property
Santa Ana
2.0 out of 10, (1)
2.0/10
(1)
The price is CNY1,032
CNY1,032
CNY1,135 total
includes taxes & fees
Dec 22 - Dec 23
Radisson Hotel Panama Canal
Radisson Hotel Panama Canal4.5 star property
Amador, 2.3 km from Santa Ana
8.4 out of 10, Very Good, (1004)
8.4/10
Very Good
(1004)
The price is CNY581
CNY581
CNY639 total
includes taxes & fees
Jan 3 - Jan 4, 2026
8.8 out of 10, Excellent, (415)
8.8/10
Excellent
(415)
The price is CNY672
CNY672
CNY740 total
includes taxes & fees
Dec 22 - Dec 23
8.0 out of 10, Very Good, (151)
8.0/10
Very Good
(151)
The price is CNY256
CNY256
CNY282 total
includes taxes & fees
Dec 22 - Dec 23
7.8 out of 10, Good, (108)
7.8/10
Good
(108)
9.0 out of 10, Wonderful, (4700)
9.0/10
Wonderful
(4700)
The price is CNY770
CNY770
CNY847 total
includes taxes & fees
Jan 12 - Jan 13, 2026
9.0 out of 10, Wonderful, (1007)
9.0/10
Wonderful
(1007)
The price is CNY1,051
CNY1,051
CNY1,156 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Central Hotel Panama Casco Viejo
Central Hotel Panama Casco Viejo4.0 star property
San Felipe, 0.9 km from Santa Ana
9.0 out of 10, Wonderful, (1010)
9.0/10
Wonderful
(1010)
The price is CNY1,492
CNY1,492
CNY1,641 total
includes taxes & fees
Dec 22 - Dec 23
9.0 out of 10, Wonderful, (429)
9.0/10
Wonderful
(429)
The price is CNY282
CNY282
CNY310 total
includes taxes & fees
Dec 22 - Dec 23
Hyatt Regency Panama City
Hyatt Regency Panama City4.5 star property
Campo Alegre, 3.3 km from Santa Ana
10.0 out of 10, Exceptional, (126)
10/10
Exceptional
(126)
The price is CNY1,104
CNY1,104
CNY1,214 total
includes taxes & fees
Jan 3 - Jan 4, 2026
9.2 out of 10, Wonderful, (1004)
9.2/10
Wonderful
(1004)
7.4 out of 10, Good, (590)
7.4/10
Good
(590)
The price is CNY517
CNY517
CNY569 total
includes taxes & fees
Jan 12 - Jan 13, 2026
9.4 out of 10, Exceptional, (607)
9.4/10
Exceptional
(607)
The price is CNY2,053
CNY2,053
CNY2,259 total
includes taxes & fees
Jan 4 - Jan 5, 2026
6.6 out of 10, (219)
6.6/10
(219)
8.8 out of 10, Excellent, (1055)
8.8/10
Excellent
(1055)
The price is CNY592
CNY592
CNY651 total
includes taxes & fees
Dec 22 - Dec 23
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
When is the best time to visit Santa Ana?
When is the best time to visit Santa Ana?Our prices for hotels in Santa Ana are cheapest in April
When is the best time to visit Santa Ana?
When is the best time to visit Santa Ana?
Our prices for hotels in Santa Ana are cheapest in April
Price trends for hotels in Santa Ana
Pricing is based on two traveler single night rates
Currently viewing crowd sizes and weather for December.
Typical weather for Panama City
December
High crowds
High 29°C / low 24°C. Cloudy most days.
View properties in December 29°
December, High crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Cloudy most days.
24°
30°
January, Moderate crowds, average high temperature 30 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
30°
February, High crowds, average high temperature 30 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
31°
March, High crowds, average high temperature 31 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
31°
April, Low crowds, average high temperature 31 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
30°
May, Low crowds, average high temperature 30 degrees Celsius, average low temperature 25 degrees Celsius. Rainy most days.
25°
29°
June, Low crowds, average high temperature 29 degrees Celsius, average low temperature 25 degrees Celsius. Rainy most days.
25°
29°
July, High crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
August, Moderate crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
September, Low crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
October, Moderate crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
November, Moderate crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
Monthly weather averages (˚C)
Check out reviews of Santa Ana hotels guests love
Casco View Apartments
10/10 Excellent
"We live this property and stay here whenever we are in town."
Hotel Riu Plaza Panama
10/10 Excellent
"The Riu EXCEEDED all my expectations. The customer service is definitely a 10, the breakfast is definitely a 10!! I met the kindest server Katuschka…I loved her. She would come hope to be back soon. "
W Panama
10/10 Excellent
"Excellent stay at the W Panama. Breakfast was great, room service was consistently good, and the pool area was relaxing and well maintained. The on-site shops and restaurants were convenient and high quality. Overall, a very enjoyable experience and I would definitely stay here again."
Megapolis Hotel Panamá
10/10 Excellent
"Clean room, comfortable, spacious. The breakfast was really good! "
The Executive Hotel
10/10 Excellent
"S"
Plaza Paitilla Inn Hotel
10/10 Excellent
"The staff were friendly and helpful. Check in was smooth, room was clean and had a nice view of the bay. The included breakfast buffet was great with a wide selection of foods. I would definitely recommend this hotel."
JW Marriott Panama
10/10 Excellent
"Just wonderful hotel"
Waldorf Astoria Panama
10/10 Excellent
"Amazing breakfast the 1st day, ok breakfast the 2nd day. Concierge was amazing. Loved the hotel and it's smell. Absolutely recommend! Teenage kids loved it too!"
Crowne Plaza Panama Airport by IHG
10/10 Excellent
"Yes to both"
Frequently asked questions
Is Santa Ana expensive to stay in?
You can find great hotels from CNY196 in Santa Ana to suit a range of budgets. If you're looking for an affordable stay in Santa Ana, Hostal La Cigarra is a great low-cost option. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for Santa Ana hotels?
Discover great deals on hotels in Santa Ana with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Santa Ana hotels.
Can I receive a refund if I cancel my Santa Ana hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Santa Ana hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
Is it worth staying in Santa Ana?
You're spoilt for choice with 112 hotels in the area so it's easy to find your perfect somewhere. Basing yourself in Santa Ana makes it easy to explore Panama City, including the neighborhoods of Casco Viejo and Bella Vista.
Find out more about Santa Ana
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