
Hotels in Wykoff
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Americas Best Value Inn & Suites Spring Valley
Americas Best Value Inn & Suites Spring Valley
2.0 star property
Spring Valley
8.2 out of 10, Very Good, (434)
8.2/10
Very Good
(434)
The price is CNY596
CNY596
CNY658 total
includes taxes & fees
Jan 19 - Jan 20, 2026




Stone Mill Hotel & Suites
Stone Mill Hotel & Suites
3.0 star property
Lanesboro
9.2 out of 10, Wonderful, (663)
9.2/10
Wonderful
(663)
The price is CNY737
CNY737
CNY791 total
includes taxes & fees
Dec 27 - Dec 28




America's Stay Inn Stewartville
America's Stay Inn Stewartville
2.5 star property
Stewartville
8.0 out of 10, Very Good, (419)
8.0/10
Very Good
(419)




AmericInn by Wyndham Rochester
AmericInn by Wyndham Rochester
2.0 star property
Rochester
8.8 out of 10, Excellent, (1004)
8.8/10
Excellent
(1004)
The price is CNY531
CNY531
CNY611 total
includes taxes & fees
Dec 29 - Dec 30




Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1002)
8.8/10
Excellent
(1002)
The price is CNY512
CNY512
CNY590 total
includes taxes & fees
Jan 1 - Jan 2, 2026




Hampton Inn Rochester-South
Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1001)
9.0/10
Wonderful
(1001)
The price is CNY565
CNY565
CNY650 total
includes taxes & fees
Jan 24 - Jan 25, 2026




Spark by Hilton Rochester South
Spark by Hilton Rochester South
3.0 star property
Rochester
9.4 out of 10, Exceptional, (328)
9.4/10
Exceptional
(328)
The price is CNY495
CNY495
CNY570 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Country Lodge inn
Country Lodge inn
2.0 star property
Harmony
9.0 out of 10, Wonderful, (39)
9.0/10
Wonderful
(39)
The price is CNY935
CNY935
CNY1,073 total
includes taxes & fees
Jan 1 - Jan 2, 2026




La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.2 out of 10, Good, (1022)
7.2/10
Good
(1022)
The price is CNY500
CNY500
CNY575 total
includes taxes & fees
Dec 27 - Dec 28




Econo Lodge Mayo Clinic Area
Econo Lodge Mayo Clinic Area
2.0 star property
Rochester
9.0 out of 10, Wonderful, (903)
9.0/10
Wonderful
(903)
The price is CNY474
CNY474
CNY546 total
includes taxes & fees
Jan 9 - Jan 10, 2026




Country Trails Inn & Suites
Country Trails Inn & Suites
2.0 star property
Preston
9.4 out of 10, Exceptional, (102)
9.4/10
Exceptional
(102)
The price is CNY799
CNY799
CNY882 total
includes taxes & fees
Jan 1 - Jan 2, 2026




Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (892)
8.8/10
Excellent
(892)
The price is CNY540
CNY540
CNY622 total
includes taxes & fees
Jan 24 - Jan 25, 2026




AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.2 out of 10, Very Good, (1148)
8.2/10
Very Good
(1148)
The price is CNY518
CNY518
CNY596 total
includes taxes & fees
Jan 2 - Jan 3, 2026




Quality Inn & Suites Mayo Clinic Area
Quality Inn & Suites Mayo Clinic Area
2.5 star property
Rochester
8.8 out of 10, Excellent, (833)
8.8/10
Excellent
(833)
The price is CNY474
CNY474
CNY553 total
includes taxes & fees
Jan 2 - Jan 3, 2026




Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
Rochester
8.2 out of 10, Very Good, (795)
8.2/10
Very Good
(795)
The price is CNY627
CNY627
CNY721 total
includes taxes & fees
Jan 2 - Jan 3, 2026




Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester
9.2 out of 10, Wonderful, (1004)
9.2/10
Wonderful
(1004)
The price is CNY905
CNY905
CNY1,042 total
includes taxes & fees
Dec 27 - Dec 28




Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park
8.8 out of 10, Excellent, (765)
8.8/10
Excellent
(765)
The price is CNY666
CNY666
CNY767 total
includes taxes & fees
Dec 28 - Dec 29




Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area
2.5 star property
Kutzky Park
7.8 out of 10, Good, (1001)
7.8/10
Good
(1001)
The price is CNY526
CNY526
CNY606 total
includes taxes & fees
Dec 27 - Dec 28




Hilton Garden Inn Rochester Downtown, MN
Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester
8.8 out of 10, Excellent, (853)
8.8/10
Excellent
(853)
The price is CNY751
CNY751
CNY864 total
includes taxes & fees
Jan 2 - Jan 3, 2026




Country Inn & Suites Rochester South Mayo Clinic
Country Inn & Suites Rochester South Mayo Clinic
3.0 star property
Rochester
8.4 out of 10, Very Good, (1001)
8.4/10
Very Good
(1001)
The price is CNY620
CNY620
CNY714 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Budget hotels in Wykoff and vicinity




Super 8 by Wyndham Rochester Mayo Clinic Area
Super 8 by Wyndham Rochester Mayo Clinic Area2.0 star property
Rochester
7.8 out of 10, Good, (1001)
7.8/10
Good
(1001)
The price is CNY370
CNY370
CNY426 total
includes taxes & fees
Jan 2 - Jan 3, 2026




MainStay Suites Rochester South Mayo Clinic
MainStay Suites Rochester South Mayo Clinic2.5 star property
Rochester
7.0 out of 10, Good, (90)
7.0/10
Good
(90)
The price is CNY391
CNY391
CNY451 total
includes taxes & fees
Dec 28 - Dec 29




Baymont by Wyndham Rochester Mayo Clinic Area
Baymont by Wyndham Rochester Mayo Clinic Area2.5 star property
Rochester
7.2 out of 10, Good, (721)
7.2/10
Good
(721)
The price is CNY417
CNY417
CNY481 total
includes taxes & fees
Jan 2 - Jan 3, 2026




7.6 out of 10, Good, (534)
7.6/10
Good
(534)




8.0 out of 10, Very Good, (419)
8.0/10
Very Good
(419)




9.0 out of 10, Wonderful, (903)
9.0/10
Wonderful
(903)
The price is CNY474
CNY474
CNY546 total
includes taxes & fees
Jan 9 - Jan 10, 2026




Quality Inn & Suites Mayo Clinic Area
Quality Inn & Suites Mayo Clinic Area2.5 star property
Rochester
8.8 out of 10, Excellent, (833)
8.8/10
Excellent
(833)
The price is CNY474
CNY474
CNY553 total
includes taxes & fees
Jan 2 - Jan 3, 2026




La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S3.0 star property
Rochester
7.2 out of 10, Good, (1022)
7.2/10
Good
(1022)
The price is CNY500
CNY500
CNY575 total
includes taxes & fees
Dec 27 - Dec 28




9.4 out of 10, Exceptional, (328)
9.4/10
Exceptional
(328)
The price is CNY495
CNY495
CNY570 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHG2.5 star property
Rochester
8.8 out of 10, Excellent, (1002)
8.8/10
Excellent
(1002)
The price is CNY512
CNY512
CNY590 total
includes taxes & fees
Jan 1 - Jan 2, 2026




AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic3.0 star property
Rochester
8.2 out of 10, Very Good, (1148)
8.2/10
Very Good
(1148)
The price is CNY518
CNY518
CNY596 total
includes taxes & fees
Jan 2 - Jan 3, 2026




Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area2.5 star property
Kutzky Park
7.8 out of 10, Good, (1001)
7.8/10
Good
(1001)
The price is CNY526
CNY526
CNY606 total
includes taxes & fees
Dec 27 - Dec 28




8.8 out of 10, Excellent, (1004)
8.8/10
Excellent
(1004)
The price is CNY531
CNY531
CNY611 total
includes taxes & fees
Dec 29 - Dec 30




9.0 out of 10, Wonderful, (1001)
9.0/10
Wonderful
(1001)
The price is CNY565
CNY565
CNY650 total
includes taxes & fees
Jan 24 - Jan 25, 2026




Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (892)
8.8/10
Excellent
(892)
The price is CNY540
CNY540
CNY622 total
includes taxes & fees
Jan 24 - Jan 25, 2026




Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys3.0 star property
Kutzky Park
9.2 out of 10, Wonderful, (772)
9.2/10
Wonderful
(772)
The price is CNY589
CNY589
CNY678 total
includes taxes & fees
Dec 28 - Dec 29




Americas Best Value Inn & Suites Spring Valley
Americas Best Value Inn & Suites Spring Valley2.0 star property
Spring Valley
8.2 out of 10, Very Good, (434)
8.2/10
Very Good
(434)
The price is CNY596
CNY596
CNY658 total
includes taxes & fees
Jan 19 - Jan 20, 2026




Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG2.5 star property
Kutzky Park
8.8 out of 10, Excellent, (765)
8.8/10
Excellent
(765)
The price is CNY666
CNY666
CNY767 total
includes taxes & fees
Dec 28 - Dec 29




Country Inn & Suites Rochester South Mayo Clinic
Country Inn & Suites Rochester South Mayo Clinic3.0 star property
Rochester
8.4 out of 10, Very Good, (1001)
8.4/10
Very Good
(1001)
The price is CNY620
CNY620
CNY714 total
includes taxes & fees
Jan 15 - Jan 16, 2026




Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's2.5 star property
Rochester
8.2 out of 10, Very Good, (795)
8.2/10
Very Good
(795)
The price is CNY627
CNY627
CNY721 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Wykoff
Family friendly
Pet friendly
Check out reviews of Wykoff hotels guests love

Holiday Inn Express Rochester South - Mayo Area by IHG
10/10 Excellent
"As usual Helpful and kind staff. "

Kahler Inn and Suites - Mayo Clinic Area
10/10 Excellent
"Clean room, comfortable! Check in easy! Front desk friendly and efficient!"

Hyatt House Rochester/Mayo Clinic Area
10/10 Excellent
"Room was spotless. Staff very responsive."

EVEN Hotel Rochester - Mayo Clinic Area by IHG
10/10 Excellent
"Updated, clean feeling, and I love the health focus."

Spark by Hilton Rochester South
10/10 Excellent
"Clean, quiet and helpful. Disliked the breakfast set up. I had to hunt for things, not in proper order. Otherwise a great stay."

Hampton Inn Rochester-South
10/10 Excellent
"Very good and complete! Highly recommend "

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
10/10 Excellent
"Rooms have had the large items renovated(carpets, bathroom) but the small details are not t"

Brentwood Inn & Suites
10/10 Excellent
"This was my second stay at Brentwood. Both times I found it to be very clean and the staff was friendly and helpful. It’s a nice, quiet place to stay and economical. I will stay there again. "

Kahler Grand Hotel
10/10 Excellent
"Great place to stay downtown. "
Frequently asked questions
How much does a hotel room cost in Wykoff?
You can find top hotels in Wykoff from CNY546 with options to suit your budget and needs. If you're after an affordable hotel in Wykoff that meets all of your requirements, set your filters and then sort the results by "Price: low to high".
How can I find deals and earn rewards at Wykoff hotels?
Discover great deals on Wykoff hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Wykoff hotels.
Can I book Wykoff hotels with free cancellation?
To book a refundable Wykoff hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
Can I book a refundable hotel in Wykoff?
If you're looking for the flexibility to change your plans to Wykoff, most accommodations offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Wykoff be like during my visit?
The warmest months in Wykoff are usually July and August with an average temp of 68°F. January and February are the chilliest months when the average temp is 22°F. The rainiest months are June and May.
Why should I book my Wykoff hotel through Hotels.com?
There are plenty of reasons to book your Wykoff travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.
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