Photo by Delen Wong

Hotels in Isla Santa María

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January 2026

February 2026

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Where to stay in Isla Santa María?

Finch Bay Galapagos Hotel

Puerto Ayora

CNY4,545 total

Feb 1 - Feb 2

Angermeyer Waterfront Inn

Puerto Ayora

CNY1,873 total

Jan 13 - Jan 14

Palo Santo Galapagos Hotel

Puerto Ayora

CNY1,658 total

Jan 12 - Jan 13

Hotel Ninfa

Puerto Ayora

Posada del Mar

Puerto Ayora

CNY490 total

Jan 13 - Jan 14

Casa del Lago Lodging House

Puerto Ayora

CNY471 total

Feb 2 - Feb 3

Standard Triple Room | In-room safe, desk, laptop workspace, iron/ironing board

Capitan Max B&B

Puerto Ayora

CNY552 total

Jan 15 - Jan 16

Standard Double or Twin Room, 1 Bedroom | Free minibar, in-room safe, desk, free WiFi

Hotel Santa Fe

Puerto Ayora

CNY1,485 total

Jan 12 - Jan 13

Hostal Costa del Pacifico

Puerto Ayora

CNY391 total

Jan 12 - Jan 13

Galapagos Chalet

Puerto Ayora

Breakfast, dinner served; local and international cuisine, ocean views

Ikala Galapagos Hotel

Puerto Ayora

El Barranco Galapagos

Puerto Ayora

CNY1,342 total

Jan 12 - Jan 13

Deluxe Double Room, Balcony | Desk, free WiFi, bed sheets

Hostal Sir Francis Drake

Puerto Ayora

CNY488 total

Jan 13 - Jan 14

Hostal Miconia

Puerto Ayora

Hotel Flamingo

Puerto Ayora

Hotel Solymar

Puerto Ayora

Grand Hotel Leon Marino Galapagos

Puerto Ayora

CNY645 total

Jan 16 - Jan 17

White House Galapagos

Puerto Ayora

Hotel Cucuve

Puerto Ayora

CNY1,689 total

Jan 13 - Jan 14

Galapagos Dreams

Puerto Ayora

CNY403 total

Jan 12 - Jan 13

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Budget hotels in Isla Santa María and vicinity

Standard Double Room, Balcony, City View | Free WiFi, wheelchair access

Hostal Casa Cascada

Puerto Ayora

CNY315 total

Jan 27 - Jan 28

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Go beyond your typical stay in Isla Santa María

Spa

Family friendly

Top landmarks in Isla Santa María

Swimming with sea turtles was one of the many amazing moments of my Galapagos adventure. Like most of the other animals, they went about their business without seeming to even notice the people around.

Post Office Bay

Post Office Bay is 4 mi (6.4 km) from central Isla Santa María, why not stop by during your stay.

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Punta Suarez

Punta Suarez is 47.5 mi (76.4 km) from central Isla Santa María, why not stop by during your stay.

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Learn more about Isla Santa María

Isla Santa María is well-known for its attractions such as Galápagos National Park and Post Office Bay.

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The circle of life. A sea lion napping near a washed up whale skeleton. The best way to see the Galapagos is island hopping on a cruise ship. #LifeAtExpedia

Check out reviews of Isla Santa María hotels guests love

Hotel el descanso del Guia

10/10 Excellent

"We are extending our stay by one day. Excellent hotel if you are prepared for the 25 minute walk to the dock Charles Darwin Ave. It is USD2 per taxi otherwise."

Fernandina Hotel & Spa Galápagos

10/10 Excellent

"We loved our stay there, near many attractions that you can easily walk to or take the taxi for ~$2 dollars to the Darwin Research Station/Pier or more if further away, staff were friendly & accommodating. Breakfasts was delicious & our rooms were newly renovated (you can ask if are available). We love that they have a pool, hot tub, ping pong table, spa, water dispensers, outdoor tables for gathering/reading/dining & ice available upon requests. Unforgettable journeys & escape home in Galapagos!! We definitely recommend & would love to return if extra blessings permits. "

Frequently asked questions

How much does a hotel room cost in Isla Santa María?

You can choose a great hotel in Isla Santa María from CNY391 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Isla Santa María that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.

How can I find deals and earn rewards at Isla Santa María hotels?

Discover great deals on Isla Santa María hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Isla Santa María hotels.

Can I book Isla Santa María hotels with free cancellation?

In order to book a refundable Isla Santa María hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

Can I book refundable hotels in Isla Santa María?

If you're looking for the flexibility to change your plans to Isla Santa María, most properties provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Isla Santa María be like during my trip?

With an average temperature of 72°F, Isla Santa María is a great place if you want to enjoy the sunshine year all year long.

Why should I book my Isla Santa María hotel through Hotels.com?

There are plenty of reasons to book your Isla Santa María travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.