Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
"Excellent tiny cabin! Marriott staff were excellent, helpful, and attentive. The extras were plentiful and really pushed our stay over the top, 5 out of 5 all the way! 15 minutes from Festus, that has pretty much anything you want to do, but wooded peace at the cabin. Will stay again!"
"The rooms were clean and the beds was nice and comfortable. The staff was friendly and air conditioning it was cold in the room when we got there so it was working. When we're in the area we'll stay there again."
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
10/10 Excellent
"Centrally located to all of our scheduled activities. Greeted by exceptional front desk clerk! Delicious breakfast served daily. Granddaughter loved the pool. Quiet and close to our main route of travel."
If you're looking for the flexibility to change your plans to De Soto, most hotels provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in De Soto be like during my trip?
July and August are typically the warmest months in De Soto when the average temp is 75°F. January and February are the coldest months when the average temperature is 38°F. April and May are the months with the most rain.
Why should I book my De Soto hotel through Hotels.com?
There are lots of reasons to book your De Soto trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.