Hotels in Santa Ana

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Jan 18 - Jan 19
Tomorrow
Jan 19 - Jan 20
Next weekend
Jan 23 - Jan 25
In two weeks
Jan 30 - Feb 1

Where to stay in Santa Ana?

Living area

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (58 reviews)
The price is CNY177
CNY194 total
includes taxes & fees
Jan 19 - Jan 20
Hostal La Cigarra
Apartment (20) | Iron/ironing board, free WiFi, bed sheets

La Manzana by Wynwood House

La Manzana by Wynwood House
3.0 star property
Santa Ana
7.2 out of 10, Good, (15 reviews)
The price is CNY458
CNY695 total
includes taxes & fees
Jan 19 - Jan 20
La Manzana by Wynwood House
Double Room | View from room

Hotel República

Hotel República
2.0 star property
Santa Ana
6.6 out of 10, (182 reviews)
Hotel República
Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (62 reviews)
Casco View Apartments
Garden

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador, 2.3 km from Santa Ana
8.6 out of 10, Excellent, (1,001 reviews)
The price is CNY521
CNY574 total
includes taxes & fees
Feb 7 - Feb 8
Radisson Hotel Panama Canal
Living area

Magnolia Inn

Magnolia Inn
2.0 star property
San Felipe, 0.7 km from Santa Ana
8.8 out of 10, Excellent, (427 reviews)
The price is CNY595
CNY654 total
includes taxes & fees
Jan 20 - Jan 21
Magnolia Inn
Terrace/patio

Hotel San Felipe

Hotel San Felipe
4.0 star property
San Felipe, 0.7 km from Santa Ana
9.4 out of 10, Exceptional, (268 reviews)
The price is CNY768
CNY845 total
includes taxes & fees
Feb 11 - Feb 12
Hotel San Felipe
Interior detail

Hotel Casa Panamá

Hotel Casa Panamá
4.0 star property
San Felipe, 0.6 km from Santa Ana
7.4 out of 10, Good, (606 reviews)
The price is CNY476
CNY523 total
includes taxes & fees
Feb 18 - Feb 19
Hotel Casa Panamá
Outdoor pool, sun loungers

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (4,847 reviews)
The price is CNY806
CNY887 total
includes taxes & fees
Feb 18 - Feb 19
Hotel Riu Plaza Panama
Lobby

The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 3.2 km from Santa Ana
9.2 out of 10, Wonderful, (1,005 reviews)
The Executive Hotel
Breakfast, lunch served; local and international cuisine, garden views

American Trade Hotel

American Trade Hotel
4.5 star property
San Felipe, 0.7 km from Santa Ana
9.4 out of 10, Exceptional, (639 reviews)
The price is CNY1,970
CNY2,167 total
includes taxes & fees
Feb 9 - Feb 10
American Trade Hotel
Front of property

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
San Felipe, 0.9 km from Santa Ana
9.2 out of 10, Wonderful, (1,005 reviews)
The price is CNY7,422
CNY8,165 total
includes taxes & fees
Feb 14 - Feb 15
Central Hotel Panama Casco Viejo
Terrace/patio

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 3.4 km from Santa Ana
9.4 out of 10, Exceptional, (2,150 reviews)
The price is CNY752
CNY828 total
includes taxes & fees
Jan 25 - Jan 26
Plaza Paitilla Inn Hotel
Elite Suite | Terrace/patio

Oasis Hotel

Oasis Hotel
3.0 star property
San Felipe, 0.6 km from Santa Ana
8.4 out of 10, Very Good, (112 reviews)
The price is CNY518
CNY569 total
includes taxes & fees
Jan 26 - Jan 27
Oasis Hotel
Outdoor pool

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Campo Alegre, 3.3 km from Santa Ana
9.8 out of 10, Exceptional, (171 reviews)
The price is CNY1,145
CNY1,259 total
includes taxes & fees
Feb 7 - Feb 8
Hyatt Regency Panama City
Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas

Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
2.1 km from Santa Ana
9.0 out of 10, Wonderful, (1,001 reviews)
The price is CNY1,122
CNY1,234 total
includes taxes & fees
Jan 31 - Feb 1
Marriott Panama Hotel
Beach/ocean view

Explora San Blas

Explora San Blas
2.0 star property
San Felipe, 0.8 km from Santa Ana
10.0 out of 10, Exceptional, (2 reviews)
Explora San Blas
Terrace/patio

Tantalo Hotel

Tantalo Hotel
3.5 star property
San Felipe, 0.7 km from Santa Ana
8.8 out of 10, Excellent, (278 reviews)
Tantalo Hotel
Classic Double Room, 1 Double Bed, Non Smoking | In-room safe, desk, soundproofing, free WiFi

Hotel Acapulco

Hotel Acapulco
3.0 star property
Calidonia, 1.3 km from Santa Ana
7.8 out of 10, Good, (130 reviews)
The price is CNY216
CNY238 total
includes taxes & fees
Jan 20 - Jan 21
Hotel Acapulco
Interior detail

Canova

Canova
3.0 star property
Calidonia, 1.4 km from Santa Ana
8.2 out of 10, Very Good, (138 reviews)
The price is CNY201
CNY221 total
includes taxes & fees
Feb 11 - Feb 12
Canova
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

When is the best time to visit Santa Ana?

Our prices for hotels in Santa Ana are cheapest in April
Price trends for hotels in Santa Ana
Pricing is based on two traveler single night rates
View properties in January
Currently viewing crowd sizes and weather for January.
Typical weather for Panama City
January
High 30°C / low 24°C. Sunny most days.
View properties in January
30°
weather_sun
January, no crowd data, average high temperature 30 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
30°
weather_sun
February, no crowd data, average high temperature 30 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
31°
weather_sun
March, no crowd data, average high temperature 31 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
31°
weather_sun
April, no crowd data, average high temperature 31 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
30°
weather_sleet
May, no crowd data, average high temperature 30 degrees Celsius, average low temperature 25 degrees Celsius. Rainy most days.
25°
29°
weather_sleet
June, no crowd data, average high temperature 29 degrees Celsius, average low temperature 25 degrees Celsius. Rainy most days.
25°
29°
weather_sleet
July, no crowd data, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
weather_sleet
August, no crowd data, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
weather_sleet
September, no crowd data, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
weather_sleet
October, no crowd data, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
weather_sleet
November, no crowd data, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
weather_cloudy
December, no crowd data, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Cloudy most days.
24°
Monthly weather averages (˚C)

Check out reviews of Santa Ana hotels guests love

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"We had a great stay for 2 nights. Clean, comfortable and great food!"
Angela 2-night trip
Posted 15 hours ago
Hotel Riu Plaza Panama

Frequently asked questions

Is Santa Ana expensive to stay in?
You can find great hotels from CNY194 in Santa Ana to suit a range of budgets. If you're looking for an affordable stay in Santa Ana, Hostal La Cigarra is a great low-cost option. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for Santa Ana hotels?
Discover great deals on hotels in Santa Ana with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Santa Ana hotels.
Can I receive a refund if I cancel my Santa Ana hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Santa Ana hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
Is it worth staying in Santa Ana?
You're spoilt for choice with 108 hotels in the area so it's easy to find your perfect somewhere. Basing yourself in Santa Ana makes it easy to explore Panama City, including the neighborhoods of Casco Viejo and Bella Vista.
Find out more about Santa Ana