Hotels in Santa Ana
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Where to stay in Santa Ana?
7.6 out of 10, Good, (55)
7.6/10
Good
(55)
The price is CNY178
CNY178
CNY195 total
includes taxes & fees
Jan 4 - Jan 5, 2026
9.2 out of 10, Wonderful, (57)
9.2/10
Wonderful
(57)
6.6 out of 10, (182)
6.6/10
(182)
7.2 out of 10, Good, (15)
7.2/10
Good
(15)
The price is CNY479
CNY479
CNY720 total
includes taxes & fees
Dec 29 - Dec 30
6.0 out of 10, (11)
6.0/10
(11)
Room-sofa Bed Stay Rooftop Pool & Gym, A
Room-sofa Bed Stay Rooftop Pool & Gym, A2.0 star property
Santa Ana
2.0 out of 10, (1)
2.0/10
(1)
The price is CNY1,032
CNY1,032
CNY1,136 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Radisson Hotel Panama Canal
Radisson Hotel Panama Canal4.5 star property
Amador, 2.3 km from Santa Ana
8.4 out of 10, Very Good, (1002)
8.4/10
Very Good
(1002)
The price is CNY578
CNY578
CNY635 total
includes taxes & fees
Jan 7 - Jan 8, 2026
8.8 out of 10, Excellent, (420)
8.8/10
Excellent
(420)
The price is CNY541
CNY541
CNY595 total
includes taxes & fees
Jan 5 - Jan 6, 2026
8.6 out of 10, Excellent, (109)
8.6/10
Excellent
(109)
The price is CNY520
CNY520
CNY572 total
includes taxes & fees
Jan 18 - Jan 19, 2026
8.8 out of 10, Excellent, (276)
8.8/10
Excellent
(276)
7.4 out of 10, Good, (592)
7.4/10
Good
(592)
The price is CNY455
CNY455
CNY501 total
includes taxes & fees
Jan 28 - Jan 29, 2026
9.2 out of 10, Wonderful, (1009)
9.2/10
Wonderful
(1009)
9.4 out of 10, Exceptional, (254)
9.4/10
Exceptional
(254)
The price is CNY817
CNY817
CNY899 total
includes taxes & fees
Jan 7 - Jan 8, 2026
9.0 out of 10, Wonderful, (4729)
9.0/10
Wonderful
(4729)
The price is CNY858
CNY858
CNY944 total
includes taxes & fees
Jan 12 - Jan 13, 2026
8.2 out of 10, Very Good, (909)
8.2/10
Very Good
(909)
The price is CNY355
CNY355
CNY390 total
includes taxes & fees
Dec 29 - Dec 30
9.0 out of 10, Wonderful, (1000)
9.0/10
Wonderful
(1000)
The price is CNY1,128
CNY1,128
CNY1,241 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Hyatt Regency Panama City
Hyatt Regency Panama City4.5 star property
Campo Alegre, 3.3 km from Santa Ana
10.0 out of 10, Exceptional, (139)
10/10
Exceptional
(139)
The price is CNY1,098
CNY1,098
CNY1,208 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals
Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals3.5 star property
Calidonia, 1.4 km from Santa Ana
7.2 out of 10, Good, (149)
7.2/10
Good
(149)
The price is CNY378
CNY378
CNY416 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Amarla Boutique Hotel Casco Viejo
Amarla Boutique Hotel Casco Viejo3.0 star property
San Felipe, 0.9 km from Santa Ana
9.6 out of 10, Exceptional, (106)
9.6/10
Exceptional
(106)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
When is the best time to visit Santa Ana?
When is the best time to visit Santa Ana?Our prices for hotels in Santa Ana are cheapest in April
When is the best time to visit Santa Ana?
When is the best time to visit Santa Ana?
Our prices for hotels in Santa Ana are cheapest in April
Price trends for hotels in Santa Ana
Pricing is based on two traveler single night rates
Currently viewing crowd sizes and weather for December.
Typical weather for Panama City
December
High crowds
High 29°C / low 24°C. Cloudy most days.
View properties in December 29°
December, High crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Cloudy most days.
24°
30°
January, Moderate crowds, average high temperature 30 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
30°
February, High crowds, average high temperature 30 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
31°
March, High crowds, average high temperature 31 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
31°
April, Low crowds, average high temperature 31 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
30°
May, Low crowds, average high temperature 30 degrees Celsius, average low temperature 25 degrees Celsius. Rainy most days.
25°
29°
June, Low crowds, average high temperature 29 degrees Celsius, average low temperature 25 degrees Celsius. Rainy most days.
25°
29°
July, High crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
August, Moderate crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
September, Low crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
October, Moderate crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
November, Moderate crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
Monthly weather averages (˚C)
Check out reviews of Santa Ana hotels guests love
Hyatt Regency Panama City
10/10 Excellent
"The service was top notch. The room was very clean and the property was well maintained and in great conditions. The breakfast buffet was excellent. "
Plaza Paitilla Inn Hotel
10/10 Excellent
"Excelente todo! Ubicación, atención… limpieza, instalaciones… todo espectacular!!!!!"
Principe Hotel and Suites
10/10 Excellent
"This is probably the 20th time I've stayed here. Its always exactly what we need."
Las Americas Golden Tower Panama
10/10 Excellent
"Great hotel in Panama for both short and long stays, with super friendly, warm, and helpful staff who bring a lot of positive energy to the experience, and the colorful design makes the place feel lively and welcoming. I ended up here unexpectedly after getting stuck in Panama due to visa issues, and I was really lucky to find a hotel that recognized my VIP status, checked me in very early in the morning, and supported me when I needed it. Communication was easy since most of the staff speak some English, breakfast offered a nice mix of local and international options, and overall service was excellent. There’s still some room for improvement in room maintenance (like a few lights not working and the desk chair needing replacement), but the room itself was very spacious with great city views."
W Panama
10/10 Excellent
"staff and food are amazing "
Novotel Panama City
10/10 Excellent
"The hotel was very nice and the staff was great."
Hotel Riu Plaza Panama
10/10 Excellent
"Clean room, friendly and attentive staff, and amenities"
Decapolis Hotel Panama City
10/10 Excellent
"Good"
Megapolis Hotel Panamá
10/10 Excellent
"Best hotel I ever stayed"
Frequently asked questions
Is Santa Ana expensive to stay in?
You can find great hotels from CNY195 in Santa Ana to suit a range of budgets. If you're looking for an affordable stay in Santa Ana, Hostal La Cigarra is a great low-cost option. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for Santa Ana hotels?
Discover great deals on hotels in Santa Ana with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Santa Ana hotels.
Can I receive a refund if I cancel my Santa Ana hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Santa Ana hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
Is it worth staying in Santa Ana?
You're spoilt for choice with 112 hotels in the area so it's easy to find your perfect somewhere. Basing yourself in Santa Ana makes it easy to explore Panama City, including the neighborhoods of Casco Viejo and Bella Vista.
Find out more about Santa Ana
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